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Supercritical fluid assisted atomization introduced by hydrodynamic cavitation mixer (SAA-HCM) was used to produce lysozyme microparticles with controlled particle size distribution in the range for aerosol drug delivery. The process is based on the atomization effect of carbon dioxide. The solubilization of certain amount of carbon dioxide in the solution(More)
Supercritical fluid assisted atomization introduced by a hydrodynamic cavitation mixer (SAA-HCM) was proposed as a green technique to fabricate insulin-loaded dry powders for inhalation administration. N-trimethyl chitosan (TMC), a polymeric mucoadhesive absorption enhancer, was synthesized and successfully micronized from aqueous solution using SAA-HCM.(More)
In order to counterbalance the unfairness to rare class on using Support Vector Machine to credit assess for imbalanced dataset from commercial banks, an adjustment Method of the separating hyperplane is proposed in the paper. Based on Fisher discrimination, the projected class mean and variance are got by projecting two classes samples onto the normal(More)
In this paper, a new piezoelectric dynamic balance regulator, which can be used in motorised spindle systems, is presented. The dynamic balancing adjustment mechanism is driven by an in-plane bending vibration from an annular piezoelectric stator excited by a high-frequency sinusoidal input voltage. This device has different construction, characteristics(More)
This paper presents the modelling and analysis of a piezoelectric annular stator structure for a new in-situ dynamic balance regulator which is driven by the in-plane bending vibration of the stator. The mathematical model for the in-plane vibration is first developed using an analytical method to determine the theoretical excitation frequency. The(More)
Chitosan oligomers (O-chitosan) micrometric particles were produced from aqueous solution using a novel process, i.e. supercritical fluid assisted atomization introduced by hydrodynamic cavitation mixer (SAA-HCM). Hydrodynamic cavitation was introduced to enhance mass transfer and facilitate the mixing between SC-CO2 and liquid solution for fine particles(More)
Integrated Multi-satellite Retrievals for Global Precipitation Measurement (IMERG) is an important satellite precipitation product of Global Precipitation Measurement (GPM) mission. Quantitative information about the errors of IMERG has great significance for the data developers and end users. In order to investigate the characteristics and the source of(More)
Supercritical fluid assisted atomization introduced by a hydrodynamic cavitation mixer (SAA-HCM) was used to micronize insulin from aqueous solution without use of any organic solvents. Insulin microparticles produced under different operating conditions including solution type, solution concentration and precipitator temperature presented distinct(More)