Zhaozhi Fan

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Extracellular polymeric substances (EPS) excreted by microalgae are effective for microalgal flocculation. An auto-flocculation strategy was conducted by adding adequate glycine into the medium, stimulating EPS secretion to achieve auto-flocculation, and recycling the supernatant medium for further cultivation. Bound EPS positively corresponded with the(More)
This study investigates time-dependent associations between source strength estimated from high-density scalp electroencephalogram (EEG) and force of voluntary handgrip contraction at different intensity levels. We first estimate source strength from raw EEG signals collected during voluntary muscle contractions at different levels and then propose a(More)
Measurement error occurs in many biomedical fields. The challenges arise when errors are heteroscedastic since we literally have only one observation for each error distribution. This paper concerns the estimation of smooth distribution function when data are contaminated with heteroscedastic errors. We study two types of methods to recover the unknown(More)
In many real applications, the distribution of measurement error could vary with each subject or even with each observation so the errors are heteroscedastic. In this paper, we propose a fast algorithm using a simulation-extrapolation (SIMEX) method to recover the unknown density in the case of heteroscedastic contamination. We show the consistency of the(More)
A new method has been developed to selectively fabricate nano-gap electrodes and nano-channels by conventional lithography. Based on a sacrificial spacer process, we have successfully obtained sub-100-nm nano-gap electrodes and nano-channels and further reduced the dimensions to 20 nm by shrinking the sacrificial spacer size. Our method shows good(More)
Methicillin-resistant staphylococcus aureus (MRSA) cause nosocomial and communal infections seriously. Rapid and accurate identification of MRSA is vital for prevention of human morbidity. Matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF-MS) has been widely used for identification and typing of micro-organisms. To(More)
In this paper we study the Buckley-James estimator of accelerated failure time models with auxiliary covariates. Instead of postulating distributional assumptions on the auxiliary covariates, we use a local polynomial approximation method to accommodate them into the Buckley-James estimating equations. The regression parameters are obtained iteratively by(More)
Osteoarthritis (OA) significantly compromises the life quality of affected individuals and imposes a substantial economic burden on our society. Unfortunately the pathogenesis of the disease is till poorly understood and no effective medications have been developed. OA is a complex disease that involves both genetic and environmental influences. To(More)
Mass spectrometry (MS) method has been one of the most popular subjects in the field of microbial identification by the reason of its rapid identification and variety application. However, the biomarker of Methicillin-resistant and methicillin-susceptible Staphylococcus aureus is out of measuring range by mass spectrometer, which leads to hard to classify(More)
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