Zhaoyang Sun

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Lassa virus is an enveloped, bi-segmented RNA virus and the most prevalent and fatal of all Old World arenaviruses. Virus entry into the host cell is mediated by a tripartite surface spike complex, which is composed of two viral glycoprotein subunits, GP1 and GP2, and the stable signal peptide. Of these, GP1 binds to cellular receptors and GP2 catalyzes(More)
In past decades, pattern classification has been intensively explored in machine learning. With the in-depth exploration of machine learning in various applications, new challenges arise, which requests researchers to move from data-driven to domain-driven models by integrating domain knowledge, and to move from static to dynamic models to adapt to the(More)
A novel active terahertz imaging scheme based on the combination of fan-beam scanning and aperture synthesized reconstruction techniques is presented. In the horizontal direction, high resolution is obtained by the narrow side of the fan-beam based on real aperture focusing with special pillbox-like quasi-optics. In the vertical direction, high resolution(More)
A review for product development and knowledge management including product development process, process history, design intent and domain knowledge is presented. Modeling the product development process is the first step of the history knowledge management in the product development process. The integrated framework of the history knowledge management(More)
In applications such as target detection, domain knowledge of sensed data is often available. In this paper, we incorporate the available domain knowledge into clustering process and develop a knowledge-driven Mahalanobis distance-based ART (adaptive resonance theory) clustering algorithm. The strength of the knowledge-driven algorithm is that it can(More)
In most design activities, the design decision-making process is not recorded explicitly, which has severe impacts on design modification and design reuse. This paper presents a design thinking process model that records not only the design procedure and decisions but also the design intents behind them. The design thinking process is evolved based on the(More)
One way to reduce potentially serious problems caused by modifications to the original design is to find out design thinking process of the original designer. The knowledge structure of design thinking process is represented, which is composed of design intent, design decision, design rationale and design operation. Semi-formal structure is adopted by the(More)