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Melatonin, an indolamine mainly produced in the pineal gland, has received a great deal of attention in the last decade because of its oncostatic effects, which are due to its immunomodulatory, antiproliferative, antioxidant and its possible antiangiogenesis properties. Herein, we document its antiproliferative action on human umbilical vein endothelial(More)
Melatonin is the major secretory product of the pineal gland and is considered an important natural oncostatic agent. The anticancer activity of melatonin is due to its immunomodulatory, anti-proliferative and antioxidative effects. At present there are no direct data available as to melatonin's possible influence on angiogenesis, which is a major(More)
The primary goal of this paper is to present a unified way to transform the syntax of a logic system into certain initial algebraic structure so that it can be studied algebraically. The algebraic structures which one may choose for this purpose are various clones over a full subcategory of a category. We show that the syntax of equational logic, lambda(More)
An abstract machine is a theoretical model designed to perform a rigorous study of computation. Such a model usually consists of configurations, instructions, programs, inputs and outputs for the machine. In this paper we formalize these notions as a very simple algebraic system, called a configuration machine. If an abstract machine is defined as a(More)
Connective tissue growth factor (CTGF) is a 38-kDa cysteine-rich protein and an important regulator of angiogenesis. In order to study the role CTGF gene playing in angiogenesis, the eukaryotic expression vector of CTGF gene was constructed in this study, and the role of endogenous CTGF on migration of human umbilical vein endothelial cell (HUVECs) was(More)
The concept of a clone is central to many branches of mathematics, such as universal algebra, algebraic logic, and lambda calculus. Abstractly a clone is a category with two objects such that one is a countably infinite power of the other. Left and right algebras over a clone are covariant and contravariant functors from the category to that of sets(More)
In this paper, first-order logic is interpreted in the framework of universal algebra, using the clone theory developed in three previous papers [1] [2] and [3]. We first define the free clone T pL, Cq of terms of a first order language L over a set C of parameters in a standard way. The free right algebra FpL, Cq of formulas over the clone T pL, Cq of(More)
If V' is another model of K/k and L(V) = L(V), then we say that V and V' are proper birationally equivalent. The logarithmic Kodaira dimension K(V) oîV introduced by Iitaka (see [1]) is one of the most important proper birational invariants of V. litaka's treatment requires Hironaka's theory of resolution of singularities, and therefore at present does not(More)