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Huperzine-A in capsules and tablets for treating patients with Alzheimer disease.
AIM To compare the efficacy and safety between huperzine-A (Hup) in capsules and tablets for treating patients with Alzheimer disease (AD). METHODS Using multicenter, prospective, double-blind,… Expand
δ Tryptase Is Expressed in Multiple Human Tissues, and a Recombinant Form Has Proteolytic Activity1
Tryptases are neutral serine proteases selectively expressed in mast cells and have been implicated in the development of a number of inflammatory diseases including asthma. It has recently been… Expand
Potent inhibition of tumoral hypoxia-inducible factor 1α by albendazole
- M. Pourgholami, Z. Cai, S. Badar, Kiran T Wangoo, M. Poruchynsky, D. Morris
- BMC Cancer
- 15 April 2010
BackgroundEmerging reports suggest resistance, increased tumor invasiveness and metastasis arising from treatment with drugs targeting vascular endothelial growth factor (VEGF). It is believed that… Expand
Inhibition of Cell Proliferation, Vascular Endothelial Growth Factor and Tumor Growth by Albendazole
- M. Pourgholami, Z. Cai, L. Wang, S. Badar, M. Links, D. Morris
- Biology, Medicine
- Cancer investigation
- 1 January 2009
Vascular endothelial growth factor (VEGF) is the key molecule mediating tumor growth and malignant ascites formation. We recently reported that, in an end stage OVCAR-3 xenograft model, albendazole… Expand
The influence of ovarian cancer induced peritoneal carcinomatosis on the pharmacokinetics of albendazole in nude mice.
- M. H. Pourgholami, Z. Cai, S. W. L. Chu, P. Galettis, D. Morris
- Anticancer research
- 1 February 2010
Angiogenesis in the peritoneal cavity arising from ovarian cancer leads to peritoneal carcinomatosis, malignant ascites formation, morbidity and high mortality. Recent studies in our laboratory have… Expand
[Synthesis of 6 alpha-methyl prednisolone acetate (author's transl)].
[Microbiological hydroxylation of 6 alpha-methyl-17 alpha-hydroxy progesterone and 6 apha-methyl-17 alpha-hydroxy-11-deoxycorticosterone-21-acetate (author's transl)].
Tumor-Bearing Nude Mice OVCAR-3 Growth Factor and Malignant Ascites Formation in Albendazole : a Potent Inhibitor of Vascular Endothelial
Purpose:Angiogenesis and vesselhyperpermeability are the two factors leading to the formation of ascites.Vascular endothelial growth factor (VEGF) plays a pivotal role in malignant ascites… Expand
Abstract 383: Down-regulation of tumoral Hypoxia-Inducible Factor-1α expression in OVCAR-3 tumors by albendazole
Purpose: To determine if albendazole (ABZ) interferes with the tumoral production of HIF-1α and VEGF proteins. Procedures: Human ovarian cancer OVCAR-3 cells were exposed to hypoxic conditions and… Expand
Experimental polymyosites and preliminary trial with Chinese herbal medicine
HBsAg MAY CAUSE GUILLAIN-BARRE SYNDROME (GBS) Xu X-H, Wei X-D, Zhao M-Q, Hu Y-K, Gao X-X, Guo Y-P, Tar~ X-F. Dept. NeuroL, PUMC Hospital, Beijing 100730. Li B-L, Li J-M, Qing F-Z, ~ . ~ W-P. Academy… Expand