Zhao Wen-Li

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The promoter of miR-663 is hypermethylated in Chinese pediatric acute myeloid leukemia (AML)

Tao Yan-Fang, N S Jian, +8 authors Pan Jian
BMC Medical Genetics
2012

There is growing evidence supporting a role for microRNAs (miRNA) as targets in aberrant mechanisms of DNA hypermethylation. Epigenetic silencing of tumor suppressor miRNAs, including miR-663, which… (More)

Analyzing the gene expression profile of pediatric acute myeloid leukemia with real-time PCR arrays

Tao Yan-Fang, Wu Dong, +8 authors Pan Jian
Cancer Cell International
2012

The Real-time PCR Array System is the ideal tool for analyzing the expression of a focused panel of genes. In this study, we will analyze the gene expression profile of pediatric acute myeloid… (More)

Inhibition of the ecto-beta subunit of F1F0-ATPase inhibits proliferation and induces apoptosis in acute myeloid leukemia cell lines

Zhao Wen-Li, Wang Jian, +6 authors Pan Jian
Journal of experimental & clinical cancer…
2012

BACKGROUND Leukemia, a heterogeneous clonal disorder of hematopoietic progenitor cells, presents a world-wide health problem, especially in childhood. F1F0 ATPase, an inner mitochondrial enzyme, is… (More)

Molecular Mechanism of the Cell Death Induced by the Histone Deacetylase Pan Inhibitor LBH589 (Panobinostat) in Wilms Tumor Cells

Tao Yan-Fang, Li Zhi-Heng, +25 authors Yi-Hsien Hsieh
PloS one
2015

BACKGROUND Wilms tumor (WT) is an embryonic kidney cancer, for which histone acetylation might be a therapeutic target. LBH589, a novel targeted agent, suppresses histone deacetylases in many tumors.… (More)

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