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OBJECTIVES The aims of this study were to: 1) assess the feasibility of left ventricular (LV) vortex flow analysis using contrast echocardiography (CE); and 2) characterize and quantify LV vortex flow in normal subjects and patients with LV systolic dysfunction. BACKGROUND Vortices that form during LV filling have specific geometry and anatomical(More)
Anchor free location algorithm realizes locating the nodes in the wireless sensor networks only by the wireless transceiver equipped on each node, needs not add any other equipment or hardware. Moreover, anchor free location algorithm, which needs no anchor or only needs to elect some reference nodes during the location process, is very applicable to large(More)
Glioblastoma multiforme (GBM) is the most common primary malignant brain tumor and has a poor prognosis. We, here, report a potent antitumor effect of berberine, an isoquinoline alkaloid, on GBM. Berberine was found to have an IC50 that is much lower than temozolomide in vitro in U87, U251, and U118 glioblastoma cells. Although previous studies showed that(More)
Herein, we described a new class of uncharged non-pyridinium reactivators for nerve agent-inhibited acetylcholinesterase (AChE). Based on a dual site binding strategy, we conjugated the imidazolium aldoxime to different peripheral site ligands (PSLs) of AChE through alkyl chains. Compared with the known quaternary pyridinium reactivators, two of the(More)
This study was designed to test whether extremely low frequency electromagnetic field (ELF-EMF) could enhance the apoptosis-induction effect of X-ray radiotherapy on liver cancer cell line BEL-7402 in vitro. EMF exposure was performed inside an energized solenoid coil. X-ray irradiation was performed using a linear accelerator. Apoptosis rates of BEL-7402(More)
Activation of Wnt/β-catenin signalling is frequently observed in many types of cancer including hepatocellular carcinoma (HCC). We recently reported that cullin 4B (CUL4B), a scaffold protein that assembles CRL4B ubiquitin ligase complexes, is overexpressed in many types of solid tumours and contributes to epigenetic silencing of tumour suppressors. In this(More)
INTRODUCTION The aim of this study was to explore the environment of Echinococcus granulosus (E. granulosus) protoscolices and their relationship with their host. METHODS Proteins from the hydatid-cyst fluid (HCF) from E. granulosus were identified by proteomics. An inductively coupled plasma atomic emission spectrometer (ICP-AES) was used to determine(More)
In this paper, we propose a novel information utility description for bearings-only sensors to meet the challenge of sensor arrangement in Wireless Sensor Networks (WSN) for tracking. In order to reduce calculation, we use the probability distribution function of the predicted target state, the sensing model and the position information of sensors to define(More)
Amyloid β(Aβ) peptides are important components of plaques in Alzheimer's disease(AD). A decrease in the CSF concentration of Aβ40 and Aβ42 is a potential biomarker for incident AD. In contrast, studies on plasma Aβ40 and Aβ42 concentrations have yielded contradictory results. To explore the relationship between plasma Aβ40 and Aβ42 concentrations and AD in(More)
Mammalian cells may undergo permanent growth arrest/senescence when they incur excessive DNA damage. As a key player during DNA damage response (DDR), p53 transactivates an array of target genes that are involved in various cellular processes including the induction of cellular senescence. Chemokine receptor CXCR2 was previously reported to mediate(More)