Zhangrui Wei

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OBJECTIVE The aim of this study was to investigate whether velocity vector imaging (VVI) combined with stress echocardiography could detect potential diffused myocardial impairment of the left ventricle (LV) in diabetic rats. METHODS Thirty-five male SD rats were randomly divided into either the control group or the diabetes mellitus (DM) group (induced(More)
The purpose of this study was to investigate whether myocardial systolic dysfunction and perfusion impairment occur in diabetic rats, and to assess their relationship using velocity vector imaging (VVI) and myocardial contrast echocardiography (MCE). Forty-six rats were randomly divided into either control or the diabetes mellitus (DM) groups. DM was(More)
ETHNOPHARMACOLOGICAL RELEVANCE The flowers of Gentiana veitchiorum has been widely used in decoction form in the traditional medicine of Tibet against tussis, tracheitis, angina for their anti-inflammatory, antimicrobial and alexipharmic properties. AIM OF THE STUDY The aim of current study was to evaluate the therapeutic effects of Feining, a Chinese(More)
To investigate the characteristics of myocardial acceleration in normal left ventricular walls, velocity vector imaging was performed in 30 normal volunteers. Peak accelerations during early systole and early diastole and time to peak acceleration during early systole were calculated for each segment of the standard 16-segment model. A gradient of(More)
BACKGROUND Application of two-dimensional myocardial acceleration map derived from tissue Doppler imaging is limited by inherent angle dependency and substantial reader variability in the visualization of the origin of ventricular activation site. In this study we investigated the characteristics of myocardial acceleration in normal left ventricular (LV)(More)
OBJECTIVES The purpose of this study was to investigate how the myocardial acceleration during isovolumic contraction changed in rats with diabetic cardiomyopathy and a normal left ventricular ejection fraction (LVEF) by using velocity vector imaging. METHODS Velocity vector imaging was performed in 12 control rats and 15 rats with streptozotocin-induced(More)
We hypothesized that post-myocardial ischemia–reperfusion (I/R) remodeling associated matrix metalloproteinase-2 (MMP2) activation could be detected by using novel MMP2 targeted ultrasound imaging. We study the combination of MMP2-targeted microbubbles (TMB2) and control microbubbles with myocardium in 1 week post-I/R rats. In in vitro studies, TMB2(More)
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