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We investigated the effects that phorbol ester and diacylglycerol protein kinase C (PKC) activators had on the chemosensitivity of the human colon cancer cell line KM12L4a to Adriamycin (ADR), vincristine (VCR), and vinblastine (VLB) and on the intracellular accumulation of those drugs. Exposure of the cells to the PKC activator phorbol-12,13-dibutyrate(More)
Bioinformatics is science, which takes the computer as a tool for biological information storage, retrieval and analysis. Human Genome Project of start-up and implementation makes the biological data growth rapidly, how to obtain valid data from the mass of information is a problem which bioinformatics urgent to solve. Data mining technology used to analyze(More)
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