Zhang Sen Huang

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Corneas of diabetic patients have abnormal healing and epithelial adhesion, which may be due to alterations of the corneal extracellular matrix (ECM) and basement membrane (BM). To identify such alterations, various ECM and BM components and integrin receptors were studied by immunofluorescence on sections of normal and diabetic human corneas. Age-matched(More)
Vascular and parenchymal basement membranes (BMs) are thickened in diabetes, but alterations in individual BM components in diabetic eyes, especially in diabetic retinopathy (DR), are obscure. To identify abnormalities in the distribution of specific constituents, we analyzed cryostat sections of human eyes obtained at autopsy (seven normal, five diabetic(More)
Bone marrow mesenchymal stem cell (BM-MSC) transplantation has been suggested to be a promising method for the treatment of pulmonary arterial hypertension (PAH), a fatal disease currently without effective preventive/therapeutic strategies. However, the detailed mechanisms underlying BM-MSC therapy are largely unknown. We designed the present study to test(More)
PURPOSE Determine the tissue distribution patterns for tissue inhibitors of metalloproteinases (TIMP-1, TIMP-2, TIMP-3), gelatinase A and gelatinase B in normal and pathologic corneas. METHODS Corneas were examined by immunohistochemistry, using antibodies to TIMP-1, TIMP-2, TIMP-3, gelatinase A or gelatinase B. RESULTS In normal corneas, TIMP-1(More)
iii Preface The California Energy Commission's Public Interest Energy Research (PIER) Program supports public interest energy research and development that will help improve the quality of life in California by bringing environmentally safe, affordable, and reliable energy services and products to the marketplace. The PIER Program conducts public interest(More)
  • Z S Huang
  • Sheng li xue bao : [Acta physiologica Sinica]
  • 1996
Experiments were performed on 86 cats anesthetized with chloralose, paralyzed with gallamine triethiodide and ventilated artificially. Autospectral and coherence analysis revealed that the frontal-parietal cortex activity (EEG) and cardiac sympathetic nerve discharge (SND) were remarkably correlated in 33/44 cats. SND lagged EEG by 50 +/- 20 ms with a(More)