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BACKGROUND Infiltrating ductal carcinoma (IDC) is the most common malignant breast cancer in women, and genetic factors appear to play a significant role in the susceptibility to IDC. Alteration of DNA methylation is an epigenetic change in human cancers, including breast cancer. DNA-methyltransferase 1 (DNMT1) is a major enzyme that determines genomic(More)
OBJECTIVE Baicalin reduces the severity of severe acute pancreatitis (SAP) in a rat model. This study was carried out to examine the effect of baicalin on TNF-alpha mRNA, caspase-3 and P-selectin protein expression in the pancreas of rats with SAP. METHODS Rats with SAP were randomly assigned to untreated, baicalin-treated, octreotide-treated and(More)
Recently, mutations in the epidermal growth factor receptor (EGFR) gene were reported to correlate with EGFR tyrosine kinase inhibitor response in advanced non-small cell lung cancer (NSCLC). In this study, we attempted to detect EGFR mutations in plasma and pleural effusion samples and to make clear its correlations with gefitinib response and survival in(More)
Trans-2-phenylcyclopropylamine (referred to as PCPA hereafter, also known as tranylcypromine and Parnate) is used clinically as an antidepressant. Here, we use a new model-zebrafish (Danio rerio) to study the molecular mechanisms of its adverse reactions in vivo. Following a PCPA exposure (75 microM), embryos showed "sluggish" action (slow swim and slow(More)
MIMO-OFDM system, which is the combination of MIMO and OFDM technology, can live up to a high data transmission rate with reliability through diversity. MIMO-OFDM with STBC has excellent performance against Multi-path effects and frequency selective fading, what's more, the BER and the coding complexity is low. In this paper, a simulation model of MIMO-OFDM(More)
The programmed death-1 (PD-1) is a potent immunoregulatory molecule which is responsible for the negative regulation of T-cell activation and peripheral tolerance. In order to investigate the association between polymorphisms of PD-1 and breast cancer, a case–control study was conducted in Chinese female population consisting of 490 cases with breast cancer(More)
Satellite-based observations provide great opportunities for improving weather forecasting. Physical retrieval of atmospheric profiles from satellite observations is sensitive to the uncertainty of the first guess and other factors. In order to improve the accuracy of the physical retrieval, an ensemble methodology was developed with an emphasis on(More)
This paper proposes a generative model based semi-supervised learning method of remote sensing image classification, which makes use of both the labeled and unlabeled samples to handle the insufficient labeled training samples problems. We first train an original classifier by the small number of labeled samples alone. Then we re-train it by both the(More)
To observe the influence of Baicalin and Octreotide on liver and kidney of rats with severe acute pancreatitis (SAP) and discuss the related mechanism. SAP rats were randomly divided into model control, Baicalin treated and Octreotide treated group (n = 45). The same number of normal rats were included in sham-operated group (n = 45). In all groups, the(More)
To obtain a series of parameters describing the shape and bone thickness of the fixation route along the superior border of the arcuate line, so as to provide references for pelvic and acetabular surgery and design pelvic anatomic internal fixators. A total of 175 complete pelvic computed tomography (CT) scans of normal adult pelvises were collected. Each(More)