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Polymorphism of D-loop sequence from mitochondrial genomes of different broodstocks of Gymnocypris przewalskii(Kessler)
TLDR
PCR technique was used in an attempt to analyze the genetic structure of this fish species at mitochondrial D-loop level, in order to provide a new base for the assessment and protection of its population genetic diversities. Expand
Overexpressed circPVT1, a potential new circular RNA biomarker, contributes to doxorubicin and cisplatin resistance of osteosarcoma cells by regulating ABCB1
TLDR
Functional assays revealed that circPVT1 knockdown by siRNA could weaken the resistance to doxorubicin and cisplatin of OS cells through decreasing the expression of classical drug resistance-related gene ABCB1, which may provide a new insight into the role of circP VT1 as a biomarker for the diagnosis and treatment target of OS. Expand
Circular RNA circ_HIPK3 is down-regulated and suppresses cell proliferation, migration and invasion in osteosarcoma
TLDR
Investigation of the expression level of eight selected cancer-related circRNAs in OS cell lines, tissues and plasmas by quantitative real-time polymerase chain reaction (qRT-PCR) found that only circ_HIPK3 could stably down-regulate in the OS cell numbers than the corresponding controlled. Expand
LncRNA FENDRR sensitizes doxorubicin-resistance of osteosarcoma cells through down-regulating ABCB1 and ABCC1.
TLDR
It is demonstrated that lncRNA FENDRR may act as an inhibitory molecule of doxorubicin-resistance through down-regulating the expression of ABCB1 and ABCC1 genes in osteosarcoma cells. Expand
Screening circular RNA related to chemotherapeutic resistance in osteosarcoma by RNA sequencing.
TLDR
CircRNAs may play a role in OS chemoresistance and hsa_circ_0004674 might be a candidate target, and some pathways related to drug metabolism were significantly enriched. Expand
A novel circulating hsa_circ_0081001 act as a potential biomarker for diagnosis and prognosis of osteosarcoma
TLDR
This study suggested that circulating hsa_circ_0081001 could serve as a potential biomarker and therapeutic target for OS patients. Expand
How to Control the Cost of Construction Project
Cost control is the vital point of construction project management and enterprise administration.The relative methods,such as setting up cost control responsibility,making out reasonable constructionExpand
LncRNA FENDRR sensitizes doxorubicin-resistance of osteosarcoma cells through down-regulating ABCB1 and ABCC1
TLDR
It is demonstrated that lncRNA FENDRR may act as an inhibitory molecule of doxorubicin-resistance through down-regulating the expression of ABCB1 and ABCC1 genes in osteosarcoma cells. Expand
Fibronectin‐1 modulated by the long noncoding RNA OIP5‐AS1/miR‐200b‐3p axis contributes to doxorubicin resistance of osteosarcoma cells
TLDR
The role and potential application of the lncRNA OIP5‐AS1/miR‐200b‐3p/FN1 regulatory pathway as a promising target in treatment of OS chemo‐resistance is indicated. Expand
Antisense lncRNA FOXF1-AS1 Promotes Migration and Invasion of Osteosarcoma Cells Through the FOXF1/MMP-2/-9 Pathway
TLDR
F1-AS1 may promote migration and invasion of OS cells through the FOXF1/MMP-2/-9 pathway and provide a novel potential target in the OS therapy. Expand
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