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The mechanisms involved in gallbladder cancer metastasis still remain unclear to date. The poor understanding is due, in part, to the lack of ideal cell line and animal model for study. In the present study, 21 cell clones were isolated from the human gallbladder carcinoma cells GBC-SD and the cell clone GBC-SDHi with high invasive phenotype was fished out.(More)
OBJECTIVE To investigate the effects of mifepristone, a progesterone receptor (PR) antagonist, through the proliferation of human cholangiocarcinoma cell line FRH-0201 in vitro and the possible mechanisms involved. METHODS A two-step addition of poly-HRP anti-mouse immunoglobulin G detection system was used to detect the expression of PR in FRH-0201(More)
BACKGROUND A diverse range of cytogenetic alterations of autosomal chromosomes has been reported to date. However, few studies have addressed the abnormalities of X chromosome in hepatocellular carcinoma (HCC) except sporadic reports on the deletion of band F1 in X chromosome, and the clonal analysis of methylation pattern of the X chromosome-linked human(More)
an unsuitable representation will make the task of mining class association rules very hard for a traditional genetic algorithm (GA).But for a given dataset,it is difficult to decide which one is the best representation used in the mining progress.In this paper,we analyses the effects of different representations for a traditional GA and proposed a growing(More)
Enlightened by the analysis method of modern anthropology for sociogroup, the ethnic group evolution algorithm (EGEA)*, whose population is formed of several ethnic groups, is proposed. The ethnic group is a kind of clustering form for individuals, and represents the possible evolution trends, which are implicit in population. In EGEA, ethnic groups are(More)
In order to analyze the relationship of HLA polymorphisms and the infection of H. pylori in the population of Linqu County in Shandong Province, polymerase chain reaction with sequence-specific primers(PCR-SSP) was used to determine the alleles of HLA type I and II in 90 Hp-positive persons and 49 Hp-negative controls. The results showed that among the 68(More)
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