Zh A Donina

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The aim of this study was to characterize the pattern of inspiratory muscle fatigue and to assess the resistance to fatigue of the diaphragm (D), parasternal (PS), sternocleidomastoid (SCM), and scalene (SC) muscles. Nine healthy, untrained male subjects participated in this study. Electromyographic activity (EMG) of D, PS, SCM, and SC was recorded during(More)
Effect of posture on the hypercapnic ventilatory response was studied on the anaesthetized rats by using rebreathing techniques in the supine and head-down positions. There were no statistically significant alterations in tidal volume, frequency, minute ventilation, and P(ET)CO(2)between the head-down and supine positions during breathing at rest. However,(More)
The aim of this study was to assess the effect of inspiratory muscle training (IMT) on resistance to fatigue of the diaphragm (D), parasternal (PS), sternocleidomastoid (SCM) and scalene (SC) muscles in healthy humans during exhaustive exercise. Daily inspiratory muscle strength training was performed for 3 weeks in 10 male subjects (at a pressure threshold(More)
Effects of central hypervolemia on respiratory function and compensatory capabilities of the respiratory system were studied in the anesthetized, vagally intact or vagotomized rats. Central hypervolemia was induced by a head-down tilt on -30 degree rotation. The tilt evoked an elevation of central venous pressure (from -2+/-0.4 cmH2O to 3.9+/-0.8 cmH2O). At(More)
The ventilatory response to isocapnic hypoxia was studied using rebreathing techniques in anesthetized and tracheostomized rats both in supine and in head-down tilt position (HDT-30 degrees). Hypoxic responses were calculated by the slope of ventilation against end tidal P(A)O2. The end-tidal P(A)CO2 was kept constant by varying expired gas flow through a(More)
Two series of experiments were performed with awake rabbits to study ventilatory reactions of the respiratory system to hypoxic stimulus. Two types of tests included alternating exposure to hypoxic mixture with 14%, 12%, and 10% of O2 (for 10 min) and rebreathing (12% O2 + 4.5% CO2) with concurrent sampling of arterial blood for gas analysis. The(More)
The effect of hypercapnic ventilatory response was examined in anaesthetized spontaneously breathing rats by using rebreathing techniques both at supine and -30 degrees head-down tilt positions. No significant differences were found in the minute ventilation response between the supine and head-down positions during hypercapnic stimulations. In contrast, we(More)
In anaesthetised cats, antiorthostatic posture of the body with an inclination angle of 30 degrees increased pressure in the vena cava superior and in jugular vein. The rest of the cardio-respiratory parameters were changed insignificantly. Physical and physiological mechanisms of the blood regional redistribution in alteration of the body gravitation(More)