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Blood-Based Gene Expression Profiles Models for Classification of Subsyndromal Symptomatic Depression and Major Depressive Disorder
The finding suggested that SSD and MDD did not exhibit the same expressed genome signature with peripheral blood leukocyte, and blood cell–derived RNA of these 48 gene models may have significant value for performing diagnostic functions and classifying SSD, MDD, and healthy controls.
The prevalence of psychiatric symptoms of pregnant and non-pregnant women during the COVID-19 epidemic
- Yongjie Zhou, Hui Shi, Xiangyang Zhang
- Medicine, PsychologyTranslational Psychiatry
- 19 September 2020
It is observed that pregnancy was associated a reduced risk of symptoms of depression, anxiety, insomnia, and PTSD symptoms than non-pregnant women during the COVID-19 epidemic in China.
The prevalence and risk factors of psychological disturbances of frontline medical staff in china under the COVID-19 epidemic: Workload should be concerned
Lack of effect of brain derived neurotrophic factor (BDNF) Val66Met polymorphism on early onset schizophrenia in Chinese Han population
Association Between BDNF Val66Met Polymorphism and Cognitive Performance in Antipsychotic-Naïve Patients with Schizophrenia
- Weihong Lu, Chen Zhang, Z. Yi, Zezhi Li, Zhi-guo Wu, Y. Fang
- Psychology, MedicineJournal of Molecular Neuroscience
- 3 April 2012
Cognitive performance is broadly impaired in schizophrenic patients and the BDNF Val66Met polymorphism may be involved in the impaired executive function, which may have gender-specific characteristics.
Exploring the pathogenetic association between schizophrenia and type 2 diabetes mellitus diseases based on pathway analysis
- Yanli Liu, Zezhi Li, Meixia Zhang, Youping Deng, Z. Yi, Tieliu Shi
- Medicine, BiologyBMC Medical Genomics
- 23 January 2013
This research offers new insights into the potential mechanisms underlying the co-occurrence of SCZ and T2D, and could facilitate the inference of novel hypotheses for theCo-morbidity of the two diseases.
A study of N-methyl-D-aspartate receptor gene (GRIN2B) variants as predictors of treatment-resistant major depression
These initial findings strengthen the hypothesis that GRIN2B not only confers susceptibility to TRD, but also plays a genetic predictor for TRD in MDD patients.
The role of BDNF, NTRK2 gene and their interaction in development of treatment-resistant depression: data from multicenter, prospective, longitudinal clinic practice.
Disturbance of Oxidative Stress Parameters in Treatment-Resistant Bipolar Disorder and Their Association With Electroconvulsive Therapy Response
It is indicated that decreased SOD could be a trait rather than a state in trBD, and Oxidative stress levels are associated with illness severity and ECT response, suggesting that the mechanism of oxidative stress plays a crucial role in the pathophysiology of trBD.