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Blood-Based Gene Expression Profiles Models for Classification of Subsyndromal Symptomatic Depression and Major Depressive Disorder
TLDR
The finding suggested that SSD and MDD did not exhibit the same expressed genome signature with peripheral blood leukocyte, and blood cell–derived RNA of these 48 gene models may have significant value for performing diagnostic functions and classifying SSD, MDD, and healthy controls.
The prevalence of psychiatric symptoms of pregnant and non-pregnant women during the COVID-19 epidemic
TLDR
It is observed that pregnancy was associated a reduced risk of symptoms of depression, anxiety, insomnia, and PTSD symptoms than non-pregnant women during the COVID-19 epidemic in China.
Association Between BDNF Val66Met Polymorphism and Cognitive Performance in Antipsychotic-Naïve Patients with Schizophrenia
TLDR
Cognitive performance is broadly impaired in schizophrenic patients and the BDNF Val66Met polymorphism may be involved in the impaired executive function, which may have gender-specific characteristics.
Exploring the pathogenetic association between schizophrenia and type 2 diabetes mellitus diseases based on pathway analysis
TLDR
This research offers new insights into the potential mechanisms underlying the co-occurrence of SCZ and T2D, and could facilitate the inference of novel hypotheses for theCo-morbidity of the two diseases.
A study of N-methyl-D-aspartate receptor gene (GRIN2B) variants as predictors of treatment-resistant major depression
TLDR
These initial findings strengthen the hypothesis that GRIN2B not only confers susceptibility to TRD, but also plays a genetic predictor for TRD in MDD patients.
Disturbance of Oxidative Stress Parameters in Treatment-Resistant Bipolar Disorder and Their Association With Electroconvulsive Therapy Response
TLDR
It is indicated that decreased SOD could be a trait rather than a state in trBD, and Oxidative stress levels are associated with illness severity and ECT response, suggesting that the mechanism of oxidative stress plays a crucial role in the pathophysiology of trBD.
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