• Publications
  • Influence
Sprinter: a novel transmembrane protein required for Wg secretion and signaling
Wingless (Wg) is a secreted ligand that differentially activates gene expression in target tissues. It belongs to the Wnt family of secreted signaling molecules that regulate cell-to-cellExpand
  • 210
  • 11
  • PDF
Abnormal Expression of Collagen IV in Lens Activates Unfolded Protein Response Resulting in Cataract*
Human diseases caused by mutations in extracellular matrix genes are often associated with an increased risk of cataract and lens capsular rupture. However, the underlying mechanisms of cataractExpand
  • 66
  • 3
  • PDF
An Evi1-C/EBPβ Complex Controls Peroxisome Proliferator-Activated Receptor γ2 Gene Expression To Initiate White Fat Cell Differentiation
ABSTRACT Fibroblastic preadipocyte cells are recruited to differentiate into new adipocytes during the formation and hyperplastic growth of white adipose tissue. Peroxisome proliferator-activatedExpand
  • 30
  • 3
Unfolded Protein Response (UPR) is activated during normal lens development.
The lens of the eye is a transparent structure responsible for focusing light onto the retina. It is composed of two morphologically different cell types, epithelial cells found on the anteriorExpand
  • 30
  • 2
  • PDF
The unfolded protein response is activated in connexin 50 mutant mouse lenses.
The unfolded protein response is a set of cell signaling pathways recently recognized to be activated in the lens during both normal development and endoplasmic reticulum stress induced by eitherExpand
  • 25
  • 1
  • PDF