Zengzhen Wang

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Genetic polymorphisms of cytochrome p450 (CYP1A1) and glutathione S-transferase M1 (GSTM1) genes are thought to have significant effects on the metabolism of environmental carcinogens and thus on cancer risk, but the reported results are not always consistent. In this meta-analysis, we assessed reported studies of associations between polymorphisms of these(More)
BACKGROUND Many studies have investigated the association between the OPRM1 A118G polymorphism (rs1799971) and alcohol dependence, but the results were inconsistent. To better understand this relationship, ethnicity-specific meta-analyses were conducted. METHODS We retrieved all eligible studies published up to April 12, 2011 from the PubMed/MEDLINE,(More)
PRIMARY OBJECTIVE To examine the hospitalization costs and discharge outcomes of US children with TBI and to evaluate a severity measure, the predictive mortality likelihood level. RESEARCH DESIGN Data from the 2006 Healthcare Cost and Utilization Project Kids' Inpatient Database (KID) were used to report the national estimates and characteristics of(More)
BACKGROUND Large numbers of unmarried migrants are on the continuous move from rural-to-urban areas within China mainland, meanwhile their Reproductive Health (RH) is underserved when it is compared with the present urban RH policies. The purpose of this study is to investigate the RH knowledge and the utilization of RH services among unmarried migrants. (More)
Several studies have assessed the association between genetic polymorphisms of DRD2 and DRD4 genes and opioid dependence risk, while the results were inconsistent. We performed a meta-analysis, including 6,846 opioid dependence cases and 4,187 controls from 22 individual studies, to evaluate the roles of four variants (DRD2 -141ins/delC, rs1799732; DRD2 311(More)
Several polymorphisms (Lys(939)Gln, PAT+/- and Ala(499)Val) in the DNA nuclear excision repair gene xeroderma pigmentosum complementation group C (XPC) are thought to have significant effects on cancer risk. In this meta-analysis, we assessed reported studies of associations between three XPC polymorphisms and risk of cancers from 16 studies with 6797 cases(More)
X-ray repair cross-complementing group 1 (XRCC1), one of the >20 genes that participate in the base excision repair (BER) pathway, is thought to account for differences in lung cancer susceptibility. Our meta-analysis on 2861 cases (lung cancer patients) and 2783 controls from eight eligible studies in Chinese populations showed that for the XRCC1 Arg194Trp(More)
Many host factors or biomarkers are involved in the process of early DNA damage induced by occupational exposure to polycyclic aromatic hydrocarbons (PAH) as seen in coke-oven workers. This paper aimed to identify complicated causal interrelationship of various biomarkers using the path analysis. In this analysis, we included 235 subjects (166 coke-oven(More)
OBJECTIVES To analyse the effects of an intervention on cross-regional transfer of tuberculosis (TB) patients among floating population. METHODS On 1 October 2008, the 1-year intervention started by strengthening patients' health education, supervising medical treatments at critical phases, assisting in the transference of TB patients and persisting(More)
BACKGROUND Work-related injuries (WRIs) among construction workers have recently emerged as an important public health issue as the construction industry is booming in China. We investigated nonfatal unintentional work-related injuries and risk factors among male construction workers in central China. METHODS A purposive sampling method was used in 2008(More)