• Publications
  • Influence
Genomes of the rice pest brown planthopper and its endosymbionts reveal complex complementary contributions for host adaptation
BackgroundThe brown planthopper, Nilaparvata lugens, the most destructive pest of rice, is a typical monophagous herbivore that feeds exclusively on rice sap, which migrates over long distances.Expand
  • 220
  • 21
An iCRISPR platform for rapid, multiplexable, and inducible genome editing in human pluripotent stem cells.
Human pluripotent stem cells (hPSCs) offer a unique platform for elucidating the genes and molecular pathways that underlie complex traits and diseases. To realize this promise, methods for rapid andExpand
  • 296
  • 20
Multi-country evidence that crop diversification promotes ecological intensification of agriculture
Global food security requires increased crop productivity to meet escalating demand1–3. Current food production systems are heavily dependent on synthetic inputs that threaten the environment andExpand
  • 141
  • 12
Transcriptome Analysis of the Brown Planthopper Nilaparvata lugens
Background The brown planthopper (BPH) Nilaparvata lugens (Stål) is one of the most serious insect pests of rice in Asia. However, little is known about the mechanisms responsible for theExpand
  • 204
  • 11
Chitin synthase 1 gene and its two alternative splicing variants from two sap-sucking insects, Nilaparvata lugens and Laodelphax striatellus (Hemiptera: Delphacidae).
Chitin synthase (CHS) is an enzyme that is required for chitin formation in insect cuticles and other tissues. In this study, CHS genes from two destructive rice insect pests, the brown planthopperExpand
  • 81
  • 11
Genome Editing of Lineage Determinants in Human Pluripotent Stem Cells Reveals Mechanisms of Pancreatic Development and Diabetes.
Directed differentiation of human pluripotent stem cells (hPSCs) into somatic counterparts is a valuable tool for studying disease. However, examination of developmental mechanisms in hPSCs remainsExpand
  • 71
  • 4
RNA interference of NADPH-cytochrome P450 reductase of the rice brown planthopper, Nilaparvata lugens, increases susceptibility to insecticides.
BACKGROUND NADPH-cytochrome P450 reductase (CPR) is essential for numerous biological reactions catalysed by microsomal cytochrome P450 monooxygenases (P450s). Knockdown of CPR in several insectsExpand
  • 30
  • 4
Identification and characterization of two sensory neuron membrane proteins from Cnaphalocrocis medinalis (Lepidoptera: Pyralidae).
Sensory neuron membrane proteins (SNMPs), which are located on the dendritic membrane of olfactory neurons, were considered as important components involved in pheromone reception in insects. InExpand
  • 30
  • 2
A molecular mechanism of azoxystrobin resistance in Penicillium digitatum UV mutants and a PCR-based assay for detection of azoxystrobin-resistant strains in packing- or store-house isolates.
Sixty-five isolates of Pencillium digitatum (Pers.:Fr) Sacc., a causative agent of green mold of postharvest citrus, were collected from various locations in Zhejiang province in 2000, 2005 and 2006,Expand
  • 28
  • 2
Success in Zanzibar: eradication of tsetse.
  • 40
  • 2