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OBJECTIVE To investigate the epidemiological and clinical characteristics of a relatively large cohort of patients with oral lichen planus (OLP) from eastern China. STUDY DESIGN A total of 518 patients with histologically confirmed OLP in a long-term follow-up period (6 months-21.5 years) were retrospectively reviewed in our clinic. RESULTS Of the 518(More)
Oral cancer is the sixth most common human cancer, with a high morbidity rate and an overall 5-year survival rate of less than 50%. It is often not diagnosed until it has reached an advanced stage. Therefore, an early diagnostic and stratification strategy is of great importance for oral cancer. In the current study, urine samples of patients with oral(More)
Genistein, an isoflavone present in soy at high concentrations and being considered the primary antitumor constituent in soy, has been known to be a natural anticancer agent in in vitro studies and experimental animal models. The present study was aimed to investigate the putative chemopreventive effect of genistein on oral carcinogenesis in hamster cheek(More)
The pharmacokinetics of artesunate (AS) was studied in 3 cows, single dose of AS (5 mg/kg) were administered intravenously and the drug concentrations were determined by means of a TLC method developed in our laboratory. The plasma drug concentration-time course of AS, after the treatment with a pharmacokinetic microcomputer program MCPKP edited by(More)
OBJECTIVE To explore the effective Chinese medicine to prevent and treat oral precancerous lesions,and study the clinical therapeutic effect of Erigerontis Compound and its cellular dynamic mechanism. METHODS Select 45 volunteers suffering from leukoplakia(LK) and lichen planus(LP)who were divided int treatment and control groups. Treatment group(TG) took(More)
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