Learn More
Differentiation of skeletal muscle is affected in myotonic dystrophy (DM) patients. Analysis of cultured myoblasts from DM patients shows that DM myoblasts lose the capability to withdraw from the cell cycle during differentiation. Our data demonstrate that the expression and activity of the proteins responsible for cell cycle withdrawal are altered in DM(More)
Two new mutations in the gene encoding cytoplasmic Cu,Zn superoxide dismutase (SOD1) have been discovered in patients with familial amyotrophic lateral sclerosis (FALS). These mutations result in the truncation of most of the polypeptide segment encoded by exon 5, one by the formation of a stop codon in codon 126 (L126Z) and the other by inducing(More)
  • Z J Cai
  • 1995
Various studies suggest that some sleep functions, especially some slow wave sleep functions, are indispensable in mammals and related to brain regulation. It has been proposed that two of these functions are the adjustment of emotional balance and the processing of acquired emotional memories. During waking, the gradual accumulation of various randomly(More)
Most theories addressed to the functions of sleep are proposed primarily according to the results in one area of sleep research and may not be compatible with the results in other areas of sleep research. This paper provides a new theory regarding the functions of sleep by integratively analyzing different areas of sleep research. First, it concludes from(More)
  • Z J Cai
  • 1990
This paper proposes a new theory addressing the neural mechanism of declarative memory consolidation and retrieval. The premise of the theory is that the cortex is responsible for the storage of declarative memory while the medial temporal lobe is responsible for the consolidation and retrieval of declarative memory. The theory suggests that the medial(More)
Through inversion of the satellite remote sensing data, the values of the environmental factors in the corresponding research area are obtained. By synthesizing the influence of marine environment on damage of the structure, equipment or system, the specific affecting factors in he research area have been determined, and the inversion result has been(More)
  • 1