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Metallo-β-lactamase inhibitors by bioisosteric replacement: Preparation, activity and binding.
Bacterial resistance is compromising the use of β-lactam antibiotics including carbapenems. The main resistance mechanism against β-lactams is hydrolysis of the β-lactam ring mediated by serine- orExpand
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Structural studies of triazole inhibitors with promising inhibitor effects against antibiotic resistance metallo-β-lactamases.
Metallo-β-lactamases (MBLs) are an emerging cause of bacterial antibiotic resistance by hydrolysing all classes of β-lactams except monobactams, and the MBLs are not inhibited by clinically availableExpand
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Progressively gangrenous limbs in Korean indigenous calves
This study investigated cases of progressively necrotizing limbs in Korean indigenous calves. The recent case (Case 1) involved a 3-month old, male calf in Jeonbuk province that presented a visiblyExpand
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Oculocutaneous albinism in a calf in Korea
Albinism, characterized by absence or lack of pigmentation from the hair, skin, hooves, nasal region and the eyes is rarely seen in cattle in Korea. A 15-day old calf, approximately weighing 28 kgExpand