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Trehalose, a Novel mTOR-independent Autophagy Enhancer, Accelerates the Clearance of Mutant Huntingtin and α-Synuclein*
TLDR
It is shown that trehalose also protects cells against subsequent pro-apoptotic insults via the mitochondrial pathway, which may be relevant to the treatment of HD and related diseases, where the mutant proteins are autophagy substrates. Expand
The vertical microdistribution of cyanobacteria and green algae within desert crusts and the development of the algal crusts
TLDR
It was concluded that biomethods (such as fine species distribution and biovolume) were more precise than mineralogical approaches in judging algal crust development and thus could be a better means to measure the potentiality ofAlgal crusts in desert amelioration. Expand
Cyanobacteria-/cyanotoxin-contaminations and eutrophication status before Wuxi drinking water crisis in Lake Taihu, China.
TLDR
Investigations conducted in 2004 associated with the cyanotoxin contaminations as well as the eutrophication status in Lake Taihu indicated that, unlike the status in recent two years, cyanobacteria and chlorophyta are the co-dominance species throughout the year. Expand
STUDIES ON POLYSACCHARIDES FROM THREE EDIBLE SPECIES OF NOSTOC (CYANOBACTERIA) WITH DIFFERENT COLONY MORPHOLOGIES: COMPARISON OF MONOSACCHARIDE COMPOSITIONS AND VISCOSITIES OF POLYSACCHARIDES FROM
TLDR
The polymer preparations from field colonies had higher kinematic viscosities than those from correspondingsuspension cultures and suggested that they might be suitable for industrial uses. Expand
MiR‐145, miR‐133a and miR‐133b inhibit proliferation, migration, invasion and cell cycle progression via targeting transcription factor Sp1 in gastric cancer
TLDR
These findings demonstrated for the first time that miR‐145, miR'133a and miR •133b suppressed the proliferation, migration, invasion and cell cycle progression of gastric cancer cells through decreasing expression of Sp1 and its downstream proteins. Expand
miR-503 regulates the resistance of non-small cell lung cancer cells to cisplatin by targeting Bcl-2.
TLDR
The results suggest that miR-503 regulates cell apoptosis, at least in part by targeting Bcl-2, and thus modulates the resistance of non-small cell lung cancer cells to cisplatin. Expand
Autophagy-related Gene 7 (ATG7) and Reactive Oxygen Species/Extracellular Signal-regulated Kinase Regulate Tetrandrine-induced Autophagy in Human Hepatocellular Carcinoma*
TLDR
Results suggest that the generation of ROS plays an important role in promoting tetrandrine-induced autophagy and may be a promising clinical chemotherapeutic agent for human hepatocellular carcinoma. Expand
Structural Characterization of the Released Polysaccharide of Desiccation-Tolerant Nostoc communeDRH-1
TLDR
The structure of the viscous extracellular polysaccharide (glycan) of desiccation-tolerant Nostoc commune DRH-1 was determined through chromatographic and spectroscopic methods, suggesting that this uronic acid is an integral component of this cosmopolitan anhydrophile. Expand
miR-20a induces cisplatin resistance of a human gastric cancer cell line via targeting CYLD.
TLDR
The results of the present study suggested that miR‑20a directly repressed the expression of CYLD, leading to activation of the NFκB pathway and the downstream targets, livin and survivin, which potentially induced GC chemoresistance. Expand
Antioxidant and moisture-retention activities of the polysaccharide from Nostoc commune
The main supporting matrix of the edible Nostoc commune colony is polysaccharide, which plays important roles in protecting the cyanobacterium itself from extreme desiccation and high radiation. ToExpand
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