Zdzisław Forkasiewicz

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Abstract Objective. This study investigated the distribution of the CYP2D6 genotypes and phenotypes in a Polish population and compared the concordance of the two methods. Methods. Six hundred unrelated healthy individuals from southwestern Poland were studied. The CYP2D6 phenotype was analyzed in 300 individuals using sparteine as a model drug. The CYP2D6(More)
INTRODUCTION The relationship between genetically determined polymorphic oxidation and acetylation and susceptibility to some disease was aroused much interest. The aim of our study was to evaluate whether patients with hyperthyreosis differ from healthy persons in their ability to oxidize sparteine and acetylate sulphadimidine as model drugs. Oxidation and(More)
BACKGROUND Fine-needle aspiration biopsy (FNAB) is a recognized technique for the basic, preoperative cytological diagnosis of thyroid nodules. AIM OF THE STUDY To analyze the accuracy of FNAB in the diagnosis of thyroid cancer in patients with solitary and multiple thyroid nodules and to compare the demographic, clinical and pathological characteristics(More)
BACKGROUND The most appropriate surgical procedure for multinodular goiter (MNG) remains under debate. Incidental thyroid carcinoma (ITC) is often identified on histopathological examination after thyroidectomy performed for presumed benign MNG. AIM OF THE STUDY The aim of the study was to determine the value of radical surgery for MNG patients(More)
27 patients operated for bile duct injuries as a complication of cholecystectomy were analyzed. The methods of surgical management in "fresh" bile duct injuries and delayed complications such as stenosis of bile ducts or anastomosis and recurrent cholangitis were discussed. Mucosa to mucosa, Roux-en-Y anastomosis, without splinting drains seems to be the(More)
The aim of the study was the estimation of substernal goiter by use of three-dimensional spiral computed tomography (3-D sCT) with the contrast agent. The size and anatomy of goiter as well as its relation to surrounding tissues, particularly blood vessels was evaluated. The examination allowed good visualization of both inferior thyroid arteries. The use(More)
This is a summary of 96 Falk's Symposium, which took place in Freiburg (Germany) from 30.10 to 1.11.1996. In the article you can find the latest information about etiology and treatment of inflammatory bowel diseases. The following factors in etiopatogenesis of the diseases are described: genetical, bacterial, immunological, cigarette smoking and the(More)
Different methods of pancreatic stump management are possible to perform after pancreaticoduodenectomy. The group of 24 patients after pancreaticoduodenectomy with pancreaticojejunostomy, pancreaticogastrostomy and occlusion of the pancreatic duct by Neopren or Ethiblock were analysed. According to the literature and own results pancreatogastrostomy or(More)
Background It seems valuable for clinicians to know if diagnostics of thyroid malignancy (TM) and indications for surgery in the elderly patients differ from these in younger counterparts. Materials and Methods Retrospective analysis of the medical records of 3,749 patients surgically treated for thyroid tumor. Data of patients with histopathology(More)
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