Myocardial ischemia is the most common cause of death in the developed countries. The most severe manifestation is sudden death due to electrical instability, terminating in ventricular fibrillation or heart arrest. This study is based on experiments in which electrograms and monophasic action potentials are recorded from isolated guinea pig hearts perfused… (More)
This is a case report of an 81-year-old man who developed de novo bipolar disorder with ultrarapid cycling at the age of 80. Mood was self-rated daily over a period of ten weeks; in addition, polysomnographic and motor activity recordings were performed during a drug-free baseline period. Both depressive and hypomanic episodes had an average duration of… (More)
A young patient with FFI was started on agomelatine 25 mg to medicate nocturnal insomnia. Under this treatment sleep efficiency was improved, slow wave sleep was high and awakenings during sleep period time were far less than before. Clinically the patient was less restless during nighttime.
A method based on wavelet entropy is presented for analysis of optically recorded action potentials to assess stability of the experiment. The action potentials are recorded using fluorescent voltage-sensitive dye di-4-ANEPPS by optical means. The acquired signals are preprocessed using averaging with filtered residue method and decomposed by continuous… (More)
Early investigations on nocturnal penile tumescence (NPT) reported a close association with REM sleep; later, a less close coupling was observed under certain conditions e.g. in major depression. This supports the hypothesis that partly different mechanisms are involved in the regulation of both phenomena. In the present study, 45 male subjects suffering… (More)