Zdenka Vránová

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A study was carried out using a model of myocardial ischaemia in the dog after ligation of the left coronary artery to determine the effects of the benzodiazepines, flunitrazepam and midazolam, on the ventricular fibrillation threshold. The fibrillation threshold was measured twice within 15 min and 8 min after ligation. Fifteen minutes after the onset of(More)
Premature ventricular contractions are relatively often encountered in patients after surgical treatment of ischaemic heart disease. Mercurascan (MSC), given at 0.05 mg/kg of body weight, favourably affected both the incidence and duration of arrhythmia. Unlike other antiarrhythmics, MSC did not affect the heart rate nor blood pressure. Postoperative(More)
By means of a Immunoskintest Sevac kit the authors examined 99 patients who were subjected to heart surgery with extracorporeal circulation. In the group of patients with an index of more than 1.0 were 7% postoperative infectious complications, in the group with an index smaller than 1.0 there were 19% and in the group of patients with anergy and relative(More)
In 70 cadaverous donors the authors examined 2 hours before collection of organs the serum and urinary electrolyte levels and the creatinine and urea levels. Serious hypokaliaemia (less than 3.0 mmol/l) was found in 24.5% of the donors, hyperkaliaemia (more than 6.0 mmol/l) in 11.4%. Hyponatraemia (less than 125 mmol/l) was present in 11.4%, hypernatraemia(More)
The following results were obtained in an experimental study in the dogs in general pentobarbital anaesthesia: Lidocaine type antiarrhythmics (lidocaine, Xylocaine ASTRA, Ethmozin USSR) administered shortly before artery ligation have a pro-fibrillation effect. This effect is indirectly proportional to the ischaemic focus development. A 3rd-generation beta(More)