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  • Michael Maes, Zdeněk Fišar, Miguel Medina, Giovanni Scapagnini, Gabriel Nowak, Michael Berk
  • Medicine
  • Inflammopharmacology
  • 2011 (First Publication: 24 January 2012)
  • This paper reviews new drug targets in the treatment of depression and new drug candidates to treat depression. Depression is characterized by aberrations in six intertwined pathways: (1)Expand
  • Jan Pláteník, Zdeněk Fišar, Richard Buchal, Roman Jirák, Jiří Raboch
  • Medicine, Psychology
  • Progress in Neuro-Psychopharmacology and…
  • 2014 (First Publication: 3 April 2014)
  • BACKGROUND Glycogen synthase kinase-3β (GSK3β), cAMP-response element-binding protein (CREB) and brain-derived neurotrophic factor (BDNF) play critical roles in neuronal survival, synaptic plasticityExpand
  • Jan Vevera, Karel Valeš, Zdeněk Fišar, Jana Hroudová, Tereza Nekovářová
  • Psychology, Medicine
  • Physiology & Behavior
  • 2016 (First Publication: 1 May 2016)
  • Simvastatin and other statins (HMG-CoA (3-hydroxy-3-methylglutaryl coenzyme A) reductase inhibitors) are extensively used in clinical practices and are very effective in decreasing serum low-densityExpand
  • Zdeněk Fišar
  • Medicine, Psychology
  • Current drug abuse reviews
  • 2009
  • Progress in understanding the molecular mechanisms of cannabis action was made after discovery of cannabinoid receptors in the brain and the finding of endogenous metabolites with affinity to them.Expand