Zbigniew Janeczko

Learn More
The aim of this study was the isolation and structural elucidation of steroidal glycosides from the underground parts of ramson Allium ursinum L. The structures of the isolated compounds were established based upon chromatographic methods and 1D- and 2D-NMR, MS and IR analyses. The mixture of two steroidal saponins: (25R)-spirost-5-en-3b-ol tetrasaccharide(More)
The influence of selected steroids on the in vitro generative development of Arabidopsis thalianawas investigated. The activity of the animal steroids androsterone, androstenedione, progesterone, estrone, estriol, and 17β-estradiol was compared to 24-epibrassinolide, a member of the regulatory family of brassinosteroids. A. thaliana plants were cultured in(More)
A triterpene saponoside (LTS-4) isolated from the underground parts of Lysimachia thyrsiflora L. was defined as 3-O-{beta-D-xylopyranosyl-(1 --> 2)-beta-D-glucopyranosyl-(1 --> 4)-[beta-D-glucopyranosyl-(1 --> 2)]-alpha-L-arabinopyranosyl}-cyclamiretin A. Structure assignment was performed on the basis of spectroscopic data including homo- and heteronuclear(More)
The strongest biological activity in the Allium test was shown by Rx. Primulae. The inhibition of the linear growth of the onion roots affected with the extract from 0-2 g of Rx Primulae in 100 ml of water (W0-2) and with the 0-05% solution (S0-05) of the saponin fraction after 24 hrs was about 70% of the blanc halves. The inhibition of mitose affected with(More)
A thorough investigation of saponin fraction from the underground parts of wild garlic--Allium ursinum L. (Liliaceae) has led to the isolation of 3-[O-alpha-rhamnopyranosyl-(1-->4)-alpha-rhamnopyranosyl-(1-->4)- alpha-rhamnopyranosyl-(1-->4)-beta-glucopyranoside-(1-->)]-3 beta-hydroxypregna-5,16-dien-20-one [1]. The structure of 1 was established by(More)
Triterpene saponins (saponosides) are found in a variety of higher plants and display a wide range of pharmacological activities, including expectorant, anti-inflamatory, vasoprotective, gastroprotective and antimicrobial properties. Recently, a potential anticancer activity of saponins has been suggested by their cytotoxic, cytostatic, pro-apoptotic and(More)