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  • Yu-ren Adam Yuan, Y Z Pei, +7 authors Dinshaw J. Patel
  • Medicine, Biology
  • Molecular cell
  • 2005 (First Publication: 1 August 2005)
  • Argonaute (Ago) proteins constitute a key component of the RNA-induced silencing complex (RISC). We report the crystal structure of Aquifex aeolicus Ago (Aa-Ago) together with binding and cleavageExpand
  • Istvan Botos, Edward E Melnikov, +8 authors Alla Gustchina
  • Medicine, Chemistry
  • Journal of Biological Chemistry
  • 2004 (First Publication: 27 February 2004)
  • ATP-dependent Lon protease degrades specific short-lived regulatory proteins as well as defective and abnormal proteins in the cell. The crystal structure of the proteolytic domain (P domain) of theExpand