Zarna R. Dedania

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The objective of the current study was to develop a validated stability-indicating assay method (SIAM) for risperidone after subjecting it to forced decomposition under hydrolysis, oxidation, photolysis, and thermal stress conditions. The liquid chromatographic separation was achieved isocratically on a symmetry C18 column (5 μm size, 250 mm × 4.6 mm i.d.)(More)
This paper described validated high performance thin layer liquid chromatographic (HPTLC) method for estimation of Rosuvastatin Calcium (ROSU) and Aspirin (ASP) in capsule dosage form. The method involved separation of components by TLC on a precoated silica gel 60 F254 using a mixture of n-Hexane: Acetone: Ethyl acetate: Formic acid (6:3:1:0.2 v/v) as a(More)
The main aim of present study was to develop controlled release (CR) floating multiparticulate drug delivery system of Cefpodoxime proxetil. Microspheres were prepared by solvent evaporation technique consisting of Cefpodoxime proxetil (API) and Ethyl Cellulose and HPMC K4M as rate controlling polymer. Central composite statistical screening design was(More)
A simple, sensitive, selective, precise and stability indicating high-performance thin-layer chromatographic method for determination of quetiapine fumarate both as a bulk drug and from tablets was developed and validated as per the International Conference on Harmonization (ICH) guidelines. The HPTLC method employed aluminum plates precoated with silica(More)
Simple, precise and accurate method is described for the direct determination of Levofloxacin hemihydrate and Cefpodoxime proxetil in combined dosage form without prior separation. The method was based on HPTLC separation of the two drugs followed by the densitometry measurements of their spots at 237 nm for both drugs. The separation was carried out on(More)
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