Zanka Jurukova

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Parallel morphometric, karyometric and ultrastructural studies of the aortic wall in Okamoto-Aoki rats with short term (3-6 months) and long-term (12-16 months) spontaneous hypertension have revealed a progressive thickening of the medial layer, which is associated with an increaase in the mean nuclear area of the arterial medial smooth muscles and(More)
The arteria carotis communis of 60 Wistar rats was clamped and treated with 10% Formalin. In 45 animals wall-adherent parietal thrombi formed. The stages of organization of the thrombus was studied 5, 12, 20 and 30 days later using the light- and electron microscope. The organization of the thrombus is characterized by ingrowth of smooth muscle cells and of(More)
63 patients with cardiac tumors underwent operative treatment between January 1970 and December 1988. Three additional patients refused the operation, despite the large left atrial myxomas and obstruction of the mitral valve, recognized by echocardiography. 62 patients had benign tumors: the only malignant neoplasm was a fibrosarcoma, originating from the(More)
Differences in morphogenetic and metabolic activities of the arterial smooth muscle cells (s.m.c.) of the young rat's aorta and femoral artery were studied by histochemical, radiochemical and quantitative radioautographic methods. 3H-proline was found to be incorporated into the medial myocyte of both vessels and released into the extracellular connective(More)
27 aortic histoenzymatic activities and 6 aortic macromolecular substances were comparatively studied in spontaneous hypertensive rats (SHR) and normotensive Wistar rats (3, 5, 13 and 16 month-old). The earlier aortic changes (3rd month) were only histoenzymatic: 5 Nase and LDH were increased in the entire aorta: some oxido-reductases increase near the(More)