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Proteomic identification of differentially-expressed proteins in esophageal cancer in three ethnic groups in Xinjiang
Cathepsin D and PKM2 were for the first time observed to be dysregulated in Kazakh’s ESCC and may play a complicated role both in carcinogenesis and cell-differentiation of ESCC.
MicroRNA-137 Upregulation Increases Bladder Cancer Cell Proliferation and Invasion by Targeting PAQR3
It is found that miR-137 is up-regulated in human bladder cancer tissues and cell lines and associated with pM or pTNM stage in clinical bladder cancer patients.
New potential biomarkers in the diagnosis of esophageal squamous cell carcinoma
- Shu-Yong Xu, Zan Liu, Wen-jing Ma, I. Sheyhidin, Shutao Zheng, Xiaomei Lu
- Medicine, BiologyBiomarkers : biochemical indicators of exposure…
- 27 July 2009
The differential protein peaks analysed by SELDI-TOF-MS may contain promising serum biomarkers for screening ESCC and should be further evaluated in other populations of ESCC patients and tested against controls.
Secretomes are a potential source of molecular targets for cancer therapies and indicate that APOE is a candidate biomarker for lung adenocarcinoma metastasis
This study indicates that APOE is a potential indicator of metastatic lung ADC and that secretomes may offer a valuable resource for biomarkers of lung ADC with LNM.
Inhibition of cytoplasmic GSK-3β increases cisplatin resistance through activation of Wnt/β-catenin signaling in A549/DDP cells.
[Acceptable safety of bevacizumab therapy in combination with chemotherapy in patients with advanced lung cancer.].
- Wei Wu, Liyan Xu, Mingzhi Li
- Medicine, BiologyZhongguo fei ai za zhi = Chinese journal of lung…
- 20 March 2009
Most chemotherapy-naive patients with advanced non-squamous NSCLC treated with bevacizumab in combination with paclitaxel and carboplatin have little adverse effects that can be well tolerated.
Investigating the mechanism by which SMAD3 induces PAX6 transcription to promote the development of non-small cell lung cancer
SMAD3 promotes the progression of non-small cell lung cancer by upregulating PAX6 expression and downregulation of PAX6 mRNA and protein levels.
miR-34c plays a role of tumor suppressor in HEC‑1-B cells by targeting E2F3 protein.
It is demonstrated that miR-34c plays a role of tumor suppressor in HEC-1-B cells, and E2F3 protein may be a target of miR -34c.
C‐Myc participates in β‐catenin–mediated drug resistance in A549/DDP lung adenocarcinoma cells
C‐myc, the downstream target gene of β‐catenin, plays an important role in regulating cisplatin resistance in A549/DDP cells, and c‐Myc siRNA improved the sensitivity of A549 or DDP cells to cisPlatin.
Novel circRNA_0071196/miRNA-19b-3p/CIT axis is associated with proliferation and migration of bladder cancer
Findings indicate that circRNA-0071196 upregulates CIT levels in BCa by sponging off miRNA-19b-3p/CIT axis is a potential therapeutic target inBCa.