Zaki Shafi

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This aim of this study was to develop a microparticulate based oral drug delivery system, which could prolong gut transit time by binding via specific interactions to the gut mucus layer. Porcine gastric mucus was semi-purified and used as an antigen to raise a polyclonal antiserum in rabbits. The immunoglobulin fraction of this serum was isolated, purified(More)
Various natural products and their<lb>chemically modified derivatives have<lb>been reported to control acute and<lb>chronic inflammation as well as patho-<lb>logically excessive cell proliferation and<lb>invasion in neoplastic tissues without<lb>risk of significant toxicity. A group of<lb>different compounds characterized by the<lb>presence of multiple keto(More)
Submicron sized hydrophobic and hydrophilic albumin microspheres (MS) were prepared using a chemical crosslinking technique. Spermine was linked to the surface of the hydrophilic MS. The degree of hydrophobicity for these three types of MS was investigated using a novel technique of sedimentation volume. The surface tension of the hydrophobic MS was 31 mN(More)
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