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OBJECTIVE(S) Soluble Leishmania antigens (SLA) provide suitable protection against leishmaniasis in murine model when delivered by an appropriate delivery system. Liposomes have been shown to be suitable vaccine delivery systems against leishmaniasis, however, the phospholipase-A (PLA) activity of SLA is a drawback to prepare a stable liposomal SLA. One(More)
Rosa damascena mill L., known as Gole Mohammadi in is one of the most important species of Rosaceae family flowers. R. damascena is an ornamental plant and beside perfuming effect, several pharmacological properties including anti-HIV, antibacterial, antioxidant, antitussive, hypnotic, antidiabetic, and relaxant effect on tracheal chains have been reported(More)
Development of new generation of vaccines against leishmaniasis requires adjuvants to elicit the type and intensity of immune response needed for protection. The coupling of target-specific antibodies to the liposomal surface to create immunoliposomes has appeared as a promising way in achieving a liposome active targeting. In this study, immunoliposomes(More)
This paper presents a hybrid adaptive network based fuzzy inference system (ANFIS), computer simulation and time series algorithm to estimate and predict electricity consumption estimation. The difficulty with electricity consumption estimation modeling approach such as time series is the reason for proposing the hybrid approach of this study. The algorithm(More)
In this paper, a new support vector machine classifier with probabilistic constrains is proposed which presence probability of samples in each class is determined based on a distribution function. Noise is caused incorrect calculation of support vectors thereupon margin can not be maximized. In the proposed method, constraints boundaries and constraints(More)
OBJECTIVES Pregabalin (PGB) is a new antiepileptic drug that has received FDA approval for patient who suffers from central neuropathic pain, partial seizures, generalized anxiety disorder, fibromyalgia and sleep disorders. This study was undertaken to evaluate the possible adverse effects of PGB on the muscular system of mice. MATERIALS AND METHODS To(More)
A knowledge management (KM) system has a different schema that one of them has been studied in the present study. One of version of KM is based on artificial intelligence (AI) methods. KM based on AI has been investigated in the present work based on natural gas consumption estimation domain. Developing accurate and flexible model to natural gas consumption(More)
BACKGROUND The objective of this study was to assess mast cells and TNF-α in oral lichen planus (OLP) and oral lichenoid reactions (OLR) patients as diagnostic marker to the differential diagnosis of OLP and OLR diseases. MATERIALS AND METHODS In this cross-sectional study, samples were obtained from 30 OLP and 30 OLR patients, between June 2010 and March(More)