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Quality by design approach: Regulatory need
Abstract In this era of competition quality has been given prime magnitude; failure to meet such quality allied goals produces massive shift of company in share of market. In this contextExpand
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Stability-indicating high performance liquid chromatographic determination of atorvastatin calcium in pharmaceutical dosage form
A simple, selective, precise and stability-indicating high-performance liquid chromatographic (HPLC) method of analysis of Atorvastatin Calcium in pharmaceutical dosage form was developed andExpand
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VALIDATED RP-LC-MS/MS METHOD FOR THE SIMULTANEOUS DETERMINATION OF ALLOPURINOL AND ITS MAJOR METABOLITE, OXYPURINOL, IN HUMAN PLASMA
A rapid and highly sensitive LC-MS/MS method was developed and validated for the determination of allopurinol (AP) and its major metabolite, oxypurinol (OP) in human plasma using lamivudine as anExpand
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Development and Validation of a Dissolution Method for Pioglitazone Tablets
Dissolution testing has emerged in the pharmaceutical field as a very important tool to characterize drug product performance. Pioglitazone hydrochloride, a frequently prescribed antidiabetic, has noExpand
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Ultrasound-promoted One-Pot, Three Component Synthesis Of Novel 5-Amino-2-(4-Chlorophenyl)-7- Substituted Phenyl-8,8a-Dihydro-7H-[1,3,4]Thiadiazolo[3,2-A]Pyrimidine-6-Carbonitrile Derivatives.
Here is the report of an environment friendly, rapid, and convenient one-pot ultrasound-promoted synthesis of 5-amino-2-(4-chlorophenyl)-7- substitutedExpand
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Stability-indicating HPLC determination of tolterodine tartrate in pharmaceutical dosage form
A simple, selective, precise and stability-indicating high-performance liquid chromatographic (HPLC) method of analysis tolterodine tartrate in pharmaceutical dosage form was developed and validated.Expand
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DEVELOPMENT OF NEW PYRAZOLE HYBRIDS AS ANTITUBERCULAR AGENTS: SYNTHESIS, BIOLOGICAL EVALUATION AND MOLECULAR DOCKING STUDY
Objective: synthesis of new 1, 3-diphenyl pyrazole derivatives 9(a-f) and 10(a-f) using molecular hybridization approach for antitubercular and cytotoxic studies. Methods: The structures ofExpand
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Water-mediated oxalic acid catalysed one-pot synthesis of 2-(substituted phenyl) phthalazin-1(2H)-ones
Abstract A simple one-pot, water-mediated synthetic method for the preparation of 2-(substituted phenyl) phthalazin-1(2H)-ones is described through the reaction of phthalaldehydic acid, substitutedExpand
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One-pot three-component synthesis of 3-(α-aminobenzyl)-4-hydroxycoumarin derivatives using nanocrystalline TiO2 as reusable catalyst
An efficient nanocrystalline TiO2-catalyzed one-pot synthesis of 3-[(piperidin-1-yl)phenylmethyl]- and 3-[(morpholin-4-yl)phenylmethyl]-4-hydroxycoumarins has been developed via three-componentExpand
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