Zachary B. Canfield

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receptors enhanced activation of NF-êB as shown by increased phosphorylation of IKKá, IêBá, and NF-êB and IêBá degradation. Activation of the NF-êB pathway lead to increased secretion of pro-inflammatory cytokines, including IFN-alpha and IFNgamma, and decreased secretion of anti-inflammatory cytokines, including IL-10 and CCL2. NF-êB activation also(More)
Even with decreasing DNA synthesis costs there remains a need for inexpensive, rapid, and reliable methods for assembling synthetic DNA into larger constructs or combinatorial libraries. Advances in cloning techniques have resulted in powerful in vitro and in vivo assembly of DNA. However, monetary and time costs have limited these approaches. Here, we(More)
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