Zachary A. Matthay

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RATIONALE Receptor for advanced glycation end-products (RAGE) is one of the alveolar type I cell-associated proteins in the lung. OBJECTIVES To test the hypothesis that RAGE is a marker of alveolar epithelial type I cell injury. METHODS Rats were instilled intratracheally with 10 mg/kg lipopolysaccharide or hydrochloric acid. RAGE levels were measured(More)
New evidence indicates that neural mechanisms can down-regulate acute inflammation. In these studies, we tested the potential role of the alpha7 nicotinic acetylcholine receptor (alpha7 nAChR) in a rodent model of acid-induced acute lung injury. We first determined that the alpha7 nAChR was expressed by alveolar macrophages and lung epithelial cells. Then,(More)
New evidence indicates that neural mechanisms can down-regulate acute inflammation. In these studies, we tested the potential role of the 7 nicotinic acetylcholine receptor ( 7 nAChR) in a rodent model of acid-induced acute lung injury. We first determined that the 7 nAChR was expressed by alveolar macrophages and lung epithelial cells. Then, using an(More)
BACKGROUND The global response to HIV has started over 18 million persons on life-saving antiretroviral therapy (ART)-the vast majority in low- and middle-income countries (LMIC)-yet substantial gaps remain: up to 40% of persons living with HIV (PLHIV) know their status, while another 30% of those who enter care are inadequately retained after starting(More)
Remove both references to "proposed by Proctor et al" in the Abstract (Reference will be sufficient in the main body of the text). Change "Dissemination of standards such as those proposed by Proctor et al. for reporting can promote transparency, reproducibility and scientific accumulation" to "Dissemination of standards for reporting intervention(More)
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