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The modulation of the transient outward K+ current (Ito) by divalent cations was studied in enzymatically isolated rat ventricular myocytes with the whole cell patch-clamp technique. At holding potentials negative to -70 mV, 1 mM Cd2+ suppressed Ito, whereas, at potentials positive to -50 mV, the current was augmented. These effects were caused by shifts in(More)
Efects of parathyroid hormone on renal tubular reabsorption of calcium, sodium, and phosphate. 1973.-In order to study the relationships between sodium, calcium, and phosphate reabsorption in the proximal tubule and the effects of parathyroid hormone (PTH) on these relationships, recollection micropuncture and clearance studies were performed in dogs.(More)
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