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Renoprotective role of the vitamin D receptor in diabetic nephropathy.
1,25-Dihydroxyvitamin D3 negatively regulates the renin-angiotensin system (RAS), which plays a critical role in the development of diabetic nephropathy. We tested if mice lacking the vitamin D… Expand
1,25-Dihydroxyvitamin D3 targeting of NF-kappaB suppresses high glucose-induced MCP-1 expression in mesangial cells.
Macrophages accumulate in kidney glomeruli and interstitium of patients with diabetic nephropathy in response to monocyte chemoattractant protein-1 (MCP-1); a chemokine produced by both tubular… Expand
Photothermal ablation of pancreatic cancer cells with hybrid iron-oxide core gold-shell nanoparticles
- Yang Guo, Z. Zhang, +7 authors A. Larson
- Materials Science, Medicine
- International journal of nanomedicine
- 6 September 2013
Purpose Photothermal ablation is a minimally invasive approach, which typically involves delivery of photothermal sensitizers to targeted tissues. The purpose of our study was to demonstrate that… Expand
Three-Dimensional T2-Weighted MRI of the Human Femoral Arterial Vessel Wall at 3.0 Tesla
Objectives:To evaluate the potential use of a novel 3D turbo spin-echo (TSE) T2-weighted (T2w) technique for assessing the vessel wall in the superficial femoral artery at 3.0 T. Background:Magnetic… Expand
MRI-Monitored Transcatheter Intra-Arterial Delivery of SPIO-Labeled Natural Killer Cells to Hepatocellular Carcinoma: Preclinical Studies in a Rodent Model
ObjectivesThe objective of this study was to test the hypotheses that intra-arterial infusion allows for targeted natural killer (NK) lymphocyte delivery to hepatocellular carcinoma (HCC) and that… Expand
Gut-dependent microbial translocation induces inflammation and cardiovascular events after ST-elevation myocardial infarction
BackgroundPost-infarction cardiovascular remodeling and heart failure are the leading cause of myocardial infarction (MI)-driven death during the past decades. Experimental observations have involved… Expand
Recent advances on the roles of epidermal growth factor receptor in psoriasis.
Epidermal growth factor receptor (EGFR) is a well-characterized receptor tyrosine kinase that involved in many vital activities in cell development, such as cellular homeostasis, proliferation,… Expand
Cellular magnetic resonance imaging: potential for use in assessing aspects of cardiovascular disease.
There is rapidly increasing interest in the use of magnetic resonance imaging (MRI) to track cell migration in vivo. Iron oxide MR contrast agents can be detected at micromolar concentrations of… Expand
Efficacy, safety and tolerability of bosentan in Chinese patients with pulmonary arterial hypertension.
- Z. Jing, G. Strange, +13 authors Y. Yang
- The Journal of heart and lung transplantation…
- 1 February 2010
BACKGROUND Bosentan has an established role in the management of pulmonary arterial hypertension (PAH). This clinical trial assessed the benefits of bosentan in the Chinese population. METHODS We… Expand
Percutaneous Transhepatic Biliary Stent Implantation for Obstructive Jaundice of Perihilar Cholangiocarcinoma: A Prospective Study on Predictors of Stent Patency and Survival in 92 Patients.
- Mingwu Li, K. Li, +7 authors G. Han
- Journal of vascular and interventional radiology…
- 1 July 2016
PURPOSE To evaluate prognostic factors for stent patency and survival in patients with perihilar cholangiocarcinoma (pCCA) who underwent percutaneous biliary stent placement. MATERIALS AND METHODS… Expand