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Everolimus-Eluting Bioresorbable Scaffolds for Coronary Artery Disease.
BACKGROUND In patients with coronary artery disease who receive metallic drug-eluting coronary stents, adverse events such as late target-lesion failure may be related in part to the persistentExpand
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Proteomics and bioinformatics approaches for identification of serum biomarkers to detect breast cancer.
BACKGROUND Surface-enhanced laser desorption/ionization (SELDI) is an affinity-based mass spectrometric method in which proteins of interest are selectively adsorbed to a chemically modified surfaceExpand
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New tumor markers: CA125 and beyond
A variety of biomarkers have been developed to monitor growth of ovarian cancer and to detect disease at an early interval. CA125 (MUC16) has provided a useful serum tumor marker for monitoringExpand
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FGF-regulated Etv genes are essential for repressing Shh expression in mouse limb buds.
Anterior-posterior (A-P) patterning of the vertebrate limb is controlled by sonic hedgehog (SHH) signaling, and the precise restriction of Shh expression to the posterior limb bud is essential forExpand
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Dicer function is essential for lung epithelium morphogenesis
DICER is a key enzyme that processes microRNA and small interfering RNA precursors into their short mature forms, enabling them to regulate gene expression. Only a single Dicer gene exists in theExpand
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The Wilms tumor gene, Wt1, is required for Sox9 expression and maintenance of tubular architecture in the developing testis
  • F. Gao, S. Maiti, +6 authors V. Huff
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences
  • 8 August 2006
Mutation of the transcription factor and tumor suppressor gene WT1 results in a range of genitourinary anomalies in humans, including 46,XY gonadal dysgenesis, indicating that WT1 plays a criticalExpand
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Ovarian Cancer Biomarker Performance in Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial Specimens
Establishing a cancer screening biomarker's intended performance requires “phase III” specimens obtained in asymptomatic individuals before clinical diagnosis rather than “phase II” specimensExpand
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Independent validation of candidate breast cancer serum biomarkers identified by mass spectrometry.
BACKGROUND We previously selected a panel of 3 breast cancer biomarkers (BC1, BC2, and BC3) from serum samples collected at a single hospital based on their collective contribution to the optimalExpand
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Subcellular localization of yeast ribonucleotide reductase regulated by the DNA replication and damage checkpoint pathways
The fidelity of DNA replication and repair processes is critical for maintenance of genomic stability. Ribonucleotide reductase (RNR) catalyzes the rate-limiting step in dNTP production and thusExpand
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Subepicardial endothelial cells invade the embryonic ventricle wall to form coronary arteries
Coronary arteries bring blood flow to the heart muscle. Understanding the developmental program of the coronary arteries provides insights into the treatment of coronary artery diseases. MultipleExpand
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