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TCMID: traditional Chinese medicine integrative database for herb molecular mechanism analysis
The web-based software displays a network for integrative relationships between herbs and their treated diseases, the active ingredients and their targets, which will facilitate the study of combination therapy and understanding of the underlying mechanisms for TCM at molecular level. Expand
Blood-Based Gene Expression Profiles Models for Classification of Subsyndromal Symptomatic Depression and Major Depressive Disorder
The finding suggested that SSD and MDD did not exhibit the same expressed genome signature with peripheral blood leukocyte, and blood cell–derived RNA of these 48 gene models may have significant value for performing diagnostic functions and classifying SSD, MDD, and healthy controls. Expand
A Pilot Study of the Efficacy and Safety of Paroxetine Augmented With Risperidone, Valproate, Buspirone, Trazodone, or Thyroid Hormone in Adult Chinese Patients With Treatment-Resistant Major
  • Y. Fang, C. Yuan, +10 authors K. Gao
  • Psychology, Medicine
  • Journal of clinical psychopharmacology
  • 1 October 2011
Risperidone, valproate, buspirone, trazodone, or thyroid hormone augmentation to paroxetine 20 mg/d was effective and well tolerated in Chinese patients with TRD. Expand
Higher white blood cell counts are associated with an increased risk for metabolic syndrome and more severe psychopathology in non-diabetic patients with schizophrenia
It is suggested that WBC, a simple, readily available and inexpensive measure, may potentially be a useful marker to predict an increased risk for metabolic syndrome and more severe psychiatric symptoms in non-diabetic patients with schizophrenia. Expand
Exploring the pathogenetic association between schizophrenia and type 2 diabetes mellitus diseases based on pathway analysis
This research offers new insights into the potential mechanisms underlying the co-occurrence of SCZ and T2D, and could facilitate the inference of novel hypotheses for theCo-morbidity of the two diseases. Expand
Neuropsychological Impairment in Prodromal, First-Episode, and Chronic Psychosis: Assessing RBANS Performance
Cognitive deficits broadly emerged, and diminished functioning followed along with disease progression, and a critical need is to monitor and treat memory functioning for psychotic patients throughout all phases of the disease. Expand
Lack of effect of brain derived neurotrophic factor (BDNF) Val66Met polymorphism on early onset schizophrenia in Chinese Han population
The BDNF Val66Met polymorphism has an important effect on the age of onset of schizophrenia in a gender-specific manner and thus, further studies are required to uncover the exact role of BDNF in the development of schizophrenia. Expand
Association Between BDNF Val66Met Polymorphism and Cognitive Performance in Antipsychotic-Naïve Patients with Schizophrenia
Cognitive performance is broadly impaired in schizophrenic patients and the BDNF Val66Met polymorphism may be involved in the impaired executive function, which may have gender-specific characteristics. Expand
Influence of polymorphisms in genes SLC1A1, GRIN2B, and GRIK2 on clozapine-induced obsessive–compulsive symptoms
These results suggest that SLC1A1, GRIN2B, and interactions between the two may potentially confer a susceptibility to OC symptoms in schizophrenia patients receiving clozapine. Expand
Comparisons of the Efficacy and Tolerability of Extended-Release Venlafaxine, Mirtazapine, and Paroxetine in Treatment-Resistant Depression: A Double-Blind, Randomized Pilot Study in a Chinese
Venlafaxine-XR, mirtazapine, and paroxetine were equally effective in the treatment of Chinese patients with major depressive disorder who failed at least 2 previous antidepressant treatments. Expand