• Publications
  • Influence
Interleukin‐4 and interleukin‐10 polymorphisms and antituberculosis drug‐induced hepatotoxicity in Chinese population
TLDR
The association between IL‐4 and IL‐10 gene polymorphisms with the risk of ATDH in a Chinese population was investigated to investigate the association between pro‐ and anti‐inflammatory cytokines. Expand
The cardiovascular effects of glucagon‐like peptide‐1 receptor agonists: a trial sequential analysis of randomized controlled trials
  • S. Wu, F. Sun, +4 authors S. Zhan
  • Medicine
  • Journal of clinical pharmacy and therapeutics
  • 1 February 2014
TLDR
The purpose of this study is to systematically assess the robustness of the available evidence on the adverse cardiovascular effects of GLP‐1 receptor agonists in patients with type 2 diabetes. Expand
Perinatal undernutrition attenuates field excitatory postsynaptic potentials and influences dendritic spine density and morphology in hippocampus of male rat offspring
TLDR
Changes in the density and the types of dendritic spines in CA1 pyramidal neurons may partly explain the impaired hippocampal synaptic plasticity as well as learning and memory disturbances commonly observed during undernourished rats. Expand
The influence of ovarian stromal/theca cells during in vitro culture on steroidogenesis, proliferation and apoptosis of granulosa cells derived from the goat ovary.
  • M. Qiu, J. Liu, +5 authors Y. Zhang
  • Chemistry, Medicine
  • Reproduction in domestic animals = Zuchthygiene
  • 1 February 2014
TLDR
The results indicated that ovarian stromal/theca cells were able to stimulate oestradiol and progesterone production, promote cell proliferation and inhibit apoptosis of granulosa cells, and among all the three kinds of cells, theca cells affected strongly ongranulosa cell function, and ovarian medullaryStromal cells had the weakest effect on granULosa cells. Expand
A G-quadruplex DNA structure resolvase, RHAU, is essential for spermatogonia differentiation
TLDR
The results showed that the ablation of RHAU in germ cells caused the increase of G4 structures and thus resulted in the decrease of spermatogonial differentiation, and concluded that R HAU regulates sperMatogonia differentiation by promoting c-kit expression via directly binding to the G4 DNA motifs c-Kit promoter. Expand
Common and contrasting genomic profiles among the major human lung cancer subtypes.
TLDR
It is suggested that the AC and SCC subtypes may arise from a common cell of origin and they are driven to their distinct phenotypic end points by altered expression of a limited number of key genes such as p63, a known regulator of squamous cell differentiation. Expand
Relationship between Endothelial Nitric Oxide Synthase, Insulin Resistance and Macrovascular Disease in Patients with Acute Myocardial Infarction
TLDR
There is a close relationship between eNOS activity and the development of insulin resistance and macrovascular disease in patients with acute myocardial infarction. Expand
Degradation of methomyl by the combination of Aminobacter sp. MDW‐2 and Afipia sp. MDW‐3
TLDR
In this study, a methomyl‐degrading enrichment E1 was obtained by using the sludge from the wastewater‐treating system of a pesticide manufacturer as the original inoculant and two bacterial strains named MDW‐2 andMDW‐3 were isolated from this enrichment. Expand
Genetic polymorphisms in IL1B predict susceptibility to steroid-induced osteonecrosis of the femoral head in Chinese Han population
TLDR
It is found that IL1B rs1143630 decreased the SANFH’s risk and IL1 B rs2853550 increased the risk of steroid-induced ONFH, suggesting that IL2B gene influences the genetic susceptibility of steroids-induced OnFH. Expand
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