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Immunostimulatory activity of lactotransferrin and maturation of CD4- CD8- murine thymocytes.
Human milk lactotransferrin at a concentration ranging from 1 to 10 micrograms/ml stimulated up to 5 times the humoral immune response to sheep red blood cells, expressed as the number ofExpand
Immunosuppressive activity of cyclolinopeptide A.
It is shown that intraperitoneal, per os, as well as intravenous application of relatively large doses of CLA does not produce toxic effects and the strong immunosuppressive activity of CLA makes the peptide very interesting from the point of view of its possible utilization in medicine. Expand
Fluorescence and absorption spectroscopic properties of RNA 5'-cap analogues derived from 7-methyl-, N2,7-dimethyl- and N2,N2,7-trimethyl-guanosines.
The data clearly indicate that dynamic quenching must be taken into account when the extent of the intramolecular stacking of the latter compound is estimated by fluorescence spectroscopy. Expand
Attenuation of acridine mutagen ICR-191--DNA interactions and DNA damage by the mutagen interceptor chlorophyllin.
We have investigated the ability of chlorophyllin (CHL) to interact with acridine mutagen ICR-191 (2-methoxy-6-chloro-9-(3-(2-chloroethyl)aminopropylamino)acridine) and also its ability to decreaseExpand
In vitro blockade of bacterial phagocytosis of leukocytes by means of bacterial viruses.
Immunoregulatory properties of synthetic peptides, fragments of a proline-rich polypeptide (PRP) from ovine colostrum.
It has been previously found that a proline-rich polypeptide (PRP) isolated from ovine colostrum has a regulatory effect on the immune response. A nonapeptide fragmentExpand
Chemical and physical characterization of a proline-rich polypeptide from sheep colostrum.
The lack of effect of the polypeptide on proteolytic enzymes ruled out the possibility that it is an inhibitor of proteinases, and the proline-rich polyPEptide is not an amphipathic protein. Expand
Natural Compounds in the Human Diet and their Ability to Bind Mutagens Prevents DNA–Mutagen Intercalation
Data indicated that in order to bind 50% of the mutagen in a complex, less than twice the concentration of chlorophyllin was needed, the resveratrol concentration was 20-fold higher, while a 1000-fold or even 10,000-fold excess of xanthines were required to bind acridine orange. Expand
Immunosuppressory activity of ubiquitin fragments containing retro‐RGD sequence
It is found that the pentapeptide DGRTL is the shortest, effective immunosuppressory fragment of ubiquitin, although its potency is weaker than that of U50–59. Expand
The "interceptor" properties of chlorophyllin measured within the three-component system: intercalator-DNA-chlorophyllin.
The present data provide further support for the role of chlorophyllin as an "interceptor" that may neutralize biological activity of aromatic compounds including mutagens and antitumor drugs. Expand