Author pages are created from data sourced from our academic publisher partnerships and public sources.
- Publications
- Influence
Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease
- L. Jostins, S. Ripke, +103 authors J. Cho
- Medicine, Biology
- Nature
- 9 October 2012
Crohn’s disease and ulcerative colitis, the two common forms of inflammatory bowel disease (IBD), affect over 2.5 million people of European ancestry, with rising prevalence in other populations.… Expand
SNVer: a statistical tool for variant calling in analysis of pooled or individual next-generation sequencing data
- Z. Wei, W. Wang, Pingzhao Hu, G. Lyon, H. Hakonarson
- Biology, Medicine
- Nucleic acids research
- 3 August 2011
We develop a statistical tool SNVer for calling common and rare variants in analysis of pooled or individual next-generation sequencing (NGS) data. We formulate variant calling as a hypothesis… Expand
Analysis of shared heritability in common disorders of the brain
- V. Anttila, B. Bulik-Sullivan, +497 authors B. Crespo-Facorro
- Medicine
- Science
- 22 June 2018
Brainstorming diseases Consistent classification of neuropsychiatric diseases is problematic because it can lead to misunderstanding of etiology. The Brainstorm Consortium examined multiple… Expand
GAME: detecting cis-regulatory elements using a genetic algorithm
- Z. Wei, Shane T. Jensen
- Biology, Medicine
- Bioinform.
- 1 July 2006
TLDR
Low concordance of multiple variant-calling pipelines: practical implications for exome and genome sequencing
- Jason O'Rawe, T. Jiang, +10 authors G. Lyon
- Biology, Medicine
- Genome Medicine
- 27 March 2013
BackgroundTo facilitate the clinical implementation of genomic medicine by next-generation sequencing, it will be critically important to obtain accurate and consistent variant calls on personal… Expand
From Disease Association to Risk Assessment: An Optimistic View from Genome-Wide Association Studies on Type 1 Diabetes
- Z. Wei, K. Wang, +12 authors H. Hakonarson
- Biology, Medicine
- PLoS genetics
- 1 October 2009
Genome-wide association studies (GWAS) have been fruitful in identifying disease susceptibility loci for common and complex diseases. A remaining question is whether we can quantify individual… Expand
A Markov random field model for network-based analysis of genomic data
- Z. Wei, Hongzhe Li
- Biology, Computer Science
- Bioinform.
- 1 June 2007
TLDR
Bioremediation of Oil Spills in Cold Environments: A Review
- Si-Zhong Yang, Huijun Jin, +4 authors S. Yu
- Environmental Science
- 1 June 2009
Oil spills have become a serious problem in cold environments with the ever-increasing resource exploitation, transportation, storage, and accidental leakage of oil. Several techniques, including… Expand
Dysregulation of synaptogenesis genes antecedes motor neuron pathology in spinal muscular atrophy
- Z. Zhang, A. M. Pinto, +7 authors G. Dreyfuss
- Biology, Medicine
- Proceedings of the National Academy of Sciences
- 4 November 2013
Significance Spinal muscular atrophy (SMA), a common genetic motor neuron (MN) degenerative disease and leading hereditary cause of infant mortality, results from survival of motor neuron (SMN)… Expand
Twitter sentiment classification for measuring public health concerns
- X. Ji, Soon Ae Chun, Z. Wei, J. Geller
- Computer Science, Medicine
- Social Network Analysis and Mining
- 12 May 2015
TLDR