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BAL1 and Its Partner E3 Ligase, BBAP, Link Poly(ADP-Ribose) Activation, Ubiquitylation, and Double-Strand DNA Repair Independent of ATM, MDC1, and RNF8
ABSTRACT The BAL1 macrodomain-containing protein and its partner E3 ligase, BBAP, are overexpressed in chemotherapy-resistant lymphomas. BBAP selectively ubiquitylates histone H4 and indirectly… Expand
ALDH1A1 defines invasive cancer stem-like cells and predicts poor prognosis in patients with esophageal squamous cell carcinoma
Invasion and metastasis are the major cause of deaths in patients with esophageal cancer. In this study, we isolated cancer stem-like cells from an esophageal squamous cell carcinoma cell line EC109… Expand
Xp11.2 translocation renal cell carcinoma with NONO-TFE3 gene fusion: morphology, prognosis, and potential pitfall in detecting TFE3 gene rearrangement
Xp11 translocation renal cell carcinomas are characterized by several different translocations involving the TFE3 gene. Tumors with different specific gene fusions may have different… Expand
Synthetic circular multi-miR sponge simultaneously inhibits miR-21 and miR-93 in esophageal carcinoma
MicroRNAs (miRs) are post-transcriptional regulators involved in the initiation and progression of many tumors. Recently, naturally occurring circular RNAs (circRNAs) have been described in… Expand
Isolation and characterization of the organ-specific and light-inducible promoter of the gene encoding rubisco activase in potato (Solanum tuberosum).
- D. Qu, Y. Song, +4 authors Y. Zhang
- Biology, Medicine
- Genetics and molecular research : GMR
- 12 April 2011
Constitutive promoters have been widely used in crop biotechnology applications. Tissue-specific or inducible promoters, however, have advantages in some cases. We isolated the 731-bp 5' flanking… Expand
Design, synthesis and biological evaluation of 3',4',5'-trimethoxy flavonoid benzimidazole derivatives as potential anti-tumor agents.
A series of 3',4',5'-trimethoxy flavonoids with benzimidazole linked by different chain alkanes have been designed and synthesized. The potential activity of these compounds as anti-tumor agents was… Expand
Micro-RNA signature of lymphovascular space involvement in type 1 endometrial cancer.
- G. Canlorbe, M. Castela, +7 authors M. Ballester
- Histology and histopathology
- 1 September 2017
OBJECTIVE Lymphovascular space involvement (LVSI) is a major prognostic factor in type 1 endometrial cancer (EC). However, its use has been criticized because of poor subjectivity. MicroRNA… Expand
Vitamin D Enhances Interferon-beta Response in Multiple Sclerosis (P3.103)
Objective: Determine molecular effect of Vitamin D3 on interferon-beta response in mononuclear cells (MNC) Background: Oral vitamin D supplements have additive effects on IFN-b therapy in reducing… Expand
, RNF 8 Repair Independent of ATM , MDC 1 , and Ubiquitylation , and Double-Strand DNA Poly ( ADP-Ribose ) Activation , BAL 1 and Its Partner E 3 Ligase , BBAP , Link
Molecular cloning and expression analysis of heat shock protein 20 ( HSP 20 ) from the pearl
Small heat shock proteins (HSPs) are molecular chaperones with ATP-independent properties. They are involved in a variety of physiological and stress processes. In this study, the full-length HSP 20… Expand