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Unraveling the Possible Routes of SARS-COV-2 Invasion into the Central Nervous System
TLDR
Current data suggest that other routes, involving the nasal epithelium in general, lymphatic tissue and the CSF may also play roles in SARS-CoV-2 invasion into the CNS, and two main pathways of CNS penetration seem to be the strongest candidates, the hematogenous and the neuronal.
H. pylori and Parkinson’s disease: Meta-analyses including clinical severity
Vitamin B12, folate, and homocysteine levels and multiple sclerosis: A meta-analysis.
Brain atrophy in multiple sclerosis: mechanisms, clinical relevance and treatment options
TLDR
The different mechanisms contributing to brain atrophy are described, their clinical relevance on disease presentation and course and the effect of current or emergent DMDs onbrain atrophy and neuroprotection are described.
Body mass index and survival from amyotrophic lateral sclerosis: A meta-analysis
TLDR
BMI is significantly and inversely associated with ALS survival and this study systematically evaluated the relationship between BMI and survival in patients with ALS.
Factors associated with recurrent transient global amnesia: systematic review and pathophysiological insights
TLDR
Evidence was suggestive of a relationship between recurrence and a family orpersonal history of migraine, as well as a personal history of depression, but no connection was found between recurring and electroencephalographic abnormalities, impaired jugular venous drainage, cardiovascular risk factors, atrial fibrillation, previous cerebrovascular events, exposure to precipitating events, a positive family history of TGA and hypothyroidism.
Deciphering the role of DNA methylation in multiple sclerosis: emerging issues
TLDR
Current understanding regarding the role of DNA methylation in MS, possible therapeutic implications and future emerging issues are discussed.
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