• Publications
  • Influence
EpCAM and alpha-fetoprotein expression defines novel prognostic subtypes of hepatocellular carcinoma.
The heterogeneous nature of hepatocellular carcinoma (HCC) and the lack of appropriate biomarkers have hampered patient prognosis and treatment stratification. Recently, we have identified that aExpand
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Intratumoral balance of regulatory and cytotoxic T cells is associated with prognosis of hepatocellular carcinoma after resection.
  • Q. Gao, S. Qiu, +6 authors Z. Tang
  • Medicine
  • Journal of clinical oncology : official journal…
  • 20 June 2007
PURPOSE To investigate the prognostic value of tumor-infiltrating lymphocytes (TILs), especially regulatory T cells (Tregs), in hepatocellular carcinoma (HCC) patients after resection. PATIENTS ANDExpand
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Predicting hepatitis B virus–positive metastatic hepatocellular carcinomas using gene expression profiling and supervised machine learning
Hepatocellular carcinoma (HCC) is one of the most common and aggressive human malignancies. Its high mortality rate is mainly a result of intra-hepatic metastases. We analyzed the expression profilesExpand
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Identification of metastasis‐related microRNAs in hepatocellular carcinoma
MicroRNAs (miRNAs) have been used as cancer‐related biomarkers. Hepatocellular carcinoma (HCC) is an aggressive cancer with a dismal outcome largely due to metastasis and postsurgical recurrence. WeExpand
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A decade’s studies on metastasis of hepatocellular carcinoma
  • Z. Tang, S. Ye, +16 authors K. Liu
  • Biology, Medicine
  • Journal of Cancer Research and Clinical Oncology
  • 1 April 2004
Metastasis remains one of the major challenges before hepatocellular carcinoma (HCC) is finally conquered. This paper summarized a decade’s studies on HCC metastasis at the Liver Cancer Institute ofExpand
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Identification of microRNA‐181 by genome‐wide screening as a critical player in EpCAM–positive hepatic cancer stem cells
MicroRNAs (miRNAs) are endogenous small noncoding RNAs that regulate gene expression with functional links to tumorigenesis. Hepatocellular carcinoma (HCC) is the most common type of liver cancer,Expand
  • 475
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Stepwise metastatic human hepatocellular carcinoma cell model system with multiple metastatic potentials established through consecutive in vivo selection and studies on metastatic characteristics
  • Y. Li, Bo Tian, +5 authors Z. Tang
  • Biology, Medicine
  • Journal of Cancer Research and Clinical Oncology
  • 14 May 2004
Purpose To establish a “stepwise metastatic human hepatocellular carcinoma (HCC) cell model system” for in-depth study of the underlying mechanisms of HCC metastasis.Methods Using MHCC97— aExpand
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High expression of macrophage colony-stimulating factor in peritumoral liver tissue is associated with poor survival after curative resection of hepatocellular carcinoma.
PURPOSE To investigate prognostic values of the intratumoral and peritumoral expression of macrophage colony-stimulating factors (M-CSF) in hepatocellular carcinoma (HCC) patients after curativeExpand
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Association of TP53 mutations with stem cell-like gene expression and survival of patients with hepatocellular carcinoma.
BACKGROUND & AIMS Mutations in TP53, a tumor suppressor gene, are associated with prognosis of many cancers. However, the prognostic values of TP53 mutation sites are not known for patients withExpand
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Let-7g targets collagen type I alpha2 and inhibits cell migration in hepatocellular carcinoma.
BACKGROUND & AIMS Hepatocellular carcinoma (HCC) is an aggressive cancer with a poor prognosis mainly due to metastasis. MicroRNAs are endogenous small noncoding RNAs that regulate cellular geneExpand
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