Z. Tan

Publications92
h-index21
Citations1,433
Highly Influential Citations5
Claim Author Page
Author pages are created from data sourced from our academic publisher partnerships and public sources.

Recommended Authors

  • C. Senanayake
  • 415 Publications, 7,601 Citations
  • J. Song
  • 140 Publications, 2,298 Citations
  • Heewon Lee
  • 143 Publications, 2,273 Citations
  • N. Yee
  • 127 Publications, 2,830 Citations
  • Publications
  • Influence
Activation of TMSCN by N-heterocyclic carbenes for facile cyanosilylation of carbonyl compounds.
N-Heterocyclic carbenes were found to be highly effective organocatalysts in activating TMSCN for facile cyanosilylation of carbonyl compounds. Cyano transfer from TMSCN to aldehydes and ketones… Expand
  • 148
  • 1
Start selective and rigidify: The discovery path towards a next generation of EGFR tyrosine kinase inhibitors.
The epidermal growth factor receptor (EGFR), when carrying an activating mutation like del19 or L858R, acts as an oncogenic driver in a subset of lung tumors. While tumor responses to tyrosine kinase… Expand
  • 10
  • 1
Efficient Iron‐Catalyzed Kumada Cross‐Coupling Reactions Utilizing Flow Technology under Low Catalyst Loadings
An efficient continuous flow iron-catalyzed Kumada cross-coupling was developed for the coupling of 2-chloropyrazine and various aryl Grignard reagents in presence of low catalyst loadings (0.5… Expand
  • 10
  • 1
N-Heterocyclic Carbene-Catalyzed Silyl Enol Ether Formation.
  • 4
  • 1
A General Synthesis of Substituted Formylpyrroles from Ketones and 4-Formyloxazole.
  • 2
  • 1
Organometallic methods for the synthesis and functionalization of azaindoles.
Azaindoles (also called pyrrolopyridines) constitute essential subunits in many pharmaceutically important compounds. The synthesis of azaindoles has been a great synthetic challenge for chemists.… Expand
  • 131
Copper catalyzed asymmetric propargylation of aldehydes.
The highly enantio- and regioselective copper catalyzed asymmetric propargylation of aldehydes with a propargyl borolane reagent is reported. The methodology demonstrated broad functional group… Expand
  • 77
  • PDF
Room temperature palladium-catalyzed cross coupling of aryltrimethylammonium triflates with aryl Grignard reagents.
Aryltrimethylammonium triflates and tetrafluoroborates were found to be highly reactive electrophiles in the Pd-catalyzed cross coupling with aryl Grignard reagents. The coupling reactions proceed at… Expand
  • 88
N-heterocyclic carbene catalyzed trifluoromethylation of carbonyl compounds.
[reaction: see text]. A novel N-heterocyclic carbene (NHC) catalyzed trifluoromethylation reaction of carbonyl compounds was discovered. Both enolizable and nonenolizable aldehydes and alpha-keto… Expand
  • 91
N-heterocyclic carbene-catalyzed Mukaiyama aldol reactions.
N-Heterocyclic carbenes were shown to be highly effective catalysts to promote Mukaiyama aldol reactions. In the presence of only 0.5 mol % of N-heterocyclic carbene (5), various aldehydes and… Expand
  • 66