• Publications
  • Influence
Mosquitoes smell and avoid the insect repellent DEET
  • Z. Syed, W. Leal
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences
  • 9 September 2008
The insect repellent DEET is effective against a variety of medically important pests, but its mode of action still draws considerable debate. The widely accepted hypothesis that DEET interferes withExpand
  • 239
  • 28
  • Open Access
Pheromone reception in fruit flies expressing a moth's odorant receptor
We have expressed a male-specific, pheromone-sensitive odorant receptor (OR), BmorOR1, from the silkworm moth Bombyx mori in an “empty neuron” housed in the ab3 sensilla of a Drosophila Δhalo mutant.Expand
  • 132
  • 12
  • Open Access
Acute olfactory response of Culex mosquitoes to a human- and bird-derived attractant
  • Z. Syed, W. Leal
  • Medicine, Biology
  • Proceedings of the National Academy of Sciences
  • 3 November 2009
West Nile virus, which is transmitted by Culex mosquitoes while feeding on birds and humans, has emerged as the dominant vector borne disease in North America. We have identified natural compoundsExpand
  • 185
  • 7
  • Open Access
Knockdown of a Mosquito Odorant-binding Protein Involved in the Sensitive Detection of Oviposition Attractants
Odorant-binding proteins (OBPs) were discovered almost three decades ago, but there is still considerable debate regarding their role(s) in insect olfaction, particularly due to our inability toExpand
  • 130
  • 6
  • Open Access
Maxillary palps are broad spectrum odorant detectors in Culex quinquefasciatus.
A single type of olfactory sensilla on maxillary palps in many species of mosquitoes houses a very sensitive olfactory receptor neuron (ORN) for carbon dioxide reception. We performed extensiveExpand
  • 85
  • 4
  • Open Access
Reverse and Conventional Chemical Ecology Approaches for the Development of Oviposition Attractants for Culex Mosquitoes
Synthetic mosquito oviposition attractants are sorely needed for surveillance and control programs for Culex species, which are major vectors of pathogens causing various human diseases, includingExpand
  • 106
  • 3
  • Open Access
Kinesin and tau bind to distinct sites on microtubules.
We have used a fluorescent derivative of kinesin, AF-kinesin (kinesin conjugated with 5-(iodoacetamido)fluorescein), to investigate the binding site of kinesin on microtubules and to compare thisExpand
  • 33
  • 3
  • Open Access
Bombykol receptors in the silkworm moth and the fruit fly
Male moths are endowed with odorant receptors (ORs) to detect species-specific sex pheromones with remarkable sensitivity and selectivity. We serendipitously discovered that an endogenous OR in theExpand
  • 44
  • 3
  • Open Access
Olfactory and behavioural responses of tsetse flies, Glossina spp., to rumen metabolites
Herbivores provide tsetse flies with a blood meal, and both wild and domesticated ruminants dominate as hosts. As volatile metabolites from the rumen are regularly eructed with rumen gas, theseExpand
  • 21
  • 3
  • Open Access
Generic Insect Repellent Detector from the Fruit Fly Drosophila melanogaster
Background Insect repellents are prophylactic tools against a number of vector-borne diseases. There is growing demand for repellents outperforming DEET in cost and safety, but with the currentExpand
  • 24
  • 3
  • Open Access