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Hemoglobin-Based Blood Substitutes – Preparation Technologies and Challenges
The demand for blood transfusion has increased with improvement of medical coverage and development, but the supply of safe human blood is always a problem. For decades, researchers have been trying… Expand
Foreign output shocks, monetary rules and macroeconomic volatilities in small open economies
The 2008 financial crisis is marked by the drop in output of major industrial countries which affected small open economies in various degrees. We examine the role of three different types of… Expand
Treatment of Esophageal Cancer Based on Histology: A Surveillance Epidemiology and End Results Analysis
- D. Chang, C. Chapman, J. Shen, Z. Su, A. Koong
- American journal of clinical oncology
- 1 August 2009
Introduction:The majority of esophageal cancer is either adenocarcinoma (ACA) or squamous cell carcinoma (SCCA). Recent randomized trials suggest that definitive chemoradiotherapy may be equally… Expand
The pursuit of balance: An overview of covariate-adaptive randomization techniques in clinical trials.
Randomization is fundamental to the design and conduct of clinical trials. Simple randomization ensures independence among subject treatment assignments and prevents potential selection biases, yet… Expand
Cyberknife for brain metastases of malignant melanoma and renal cell carcinoma.
OBJECTIVE To evaluate the efficacy of CyberKnife (Accuray, Inc., Sunnyvale, CA) stereotactic radiosurgery (SRS) for patients with brain metastases of malignant melanoma and renal cell carcinoma. … Expand
CYBERKNIFE FOR BRAIN METASTASES OF MALIGNANT MELANOMA AND RENAL CELL CARCINOMA
OBJECTIVETo evaluate the efficacy of CyberKnife (Accuray, Inc., Sunnyvale, CA) stereotactic radiosurgery (SRS) for patients with brain metastases of malignant melanoma and renal cell carcinoma.… Expand
Balancing continuous and categorical baseline covariates in sequential clinical trials using the area between empirical cumulative distribution functions.
We propose a minimization approach to maintaining the balance of multiple continuous and categorical covariates in sequential clinical trials, which uses the area between the empirical cumulative distribution functions of the observed covariate values as the imbalance metric. Expand
Persisting disparities between sexes in outcomes of ruptured abdominal aortic aneurysm hospitalizations
We sought to describe and analyze discrepancies between sexes in the outcomes of patients hospitalized for ruptured abdominal aortic aneurysms (rAAA) by conducting a retrospective analysis of the… Expand
EAGLE 2006 – Multi-purpose, Multi-angle and Multi-sensor In-situ, Airborne and Space-borne Campaigns over Grassland and Forest
EAGLE2006 – an intensive field campaign for the advances in land surface hydrometeorological processes – was carried out in the Netherlands from 8th to 18th June 2006, involving 16 institutions… Expand
Futility stopping in non-inferiority trials
In a non-inferiority trial, the goal is to demonstrate that the effect of a new treatment is not inferior to the effects of the active control by a specified amount, called the non-InferiorITY margin. Expand