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Amyotrophic lateral sclerosis: T2 shortening in motor cortex at MR imaging.
Abnormal iron deposition associated with the degenerative process could be the source of T2 shortening, which is a useful MR imaging finding in the diagnosis of ALS.
Cu Zn superoxide dismutase-like immunoreactivity in Lewy body-like inclusions of sporadic amyotrophic lateral sclerosis
Amyotrophic cervical myelopathy in adolescence.
Results suggest that disproportionate shortening of the dorsal roots is further accentuated during the juvenile growth spurt, which determines the onset and self limited course of the condition, and that repeated neck flexion causes micro-trauma and relative ischaemia of anterior horn cells, which finally results in atrophy of the muscles innervated by motoneurons with long axons.
NEUROFERRITINOPATHY IN A JAPANESE FAMILY WITH A DUPLICATION IN THE FERRITIN LIGHT CHAIN GENE
A 42-year-old Japanese man first developed hand tremors in his middle teens, and generalized hypotonia, hyperextensibility, aphonia, micrographia, hyperreflexia, and cognitive impairment at age 42, and his unsteady gait with long steps, with his arms and legs dangling, seemed to be due mainly to hypotonus.
Increased sympathetic outflow to muscles in patients with amyotrophic lateral sclerosis: a comparison with other neuromuscular patients
Clinical and histopathological features of progressive-type familial amyloidotic polyneuropathy with TTR Lys54
Effect of the free radical scavenger edaravone on peripheral nerve ischemia–reperfusion injury
Edaravone was effective during the early reperfusion period, but chronic inhibition of reactive oxygen species may be detrimental for nerve regeneration after ischemia–reperfusion injury.
Sympathetic sudomotor and vasoconstrictive neural function in patients with Parkinson's disease.
Intermittent penile erection in lumbar canal stenosis
A 64-year-old man complained during the last 3 years of numbness in the lower extremities and intermittent claudication after walking 100 or 200 m, and noticed erection of the penis, which became flaccid after a few minutes rest in flexion or sitting.