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Amyotrophic lateral sclerosis: T2 shortening in motor cortex at MR imaging.
PURPOSE To determine whether decreased signal intensity of the motor cortex (T2 shortening) at magnetic resonance (MR) imaging is a useful finding for supporting the diagnosis of amyotrophic lateral… Expand
Cu/Zn superoxide dismutase-like immunoreactivity in Lewy body-like inclusions of sporadic amyotrophic lateral sclerosis.
Cu/Zn superoxide dismutase (SOD)-like immunoreactivity (LI) was found within Lewy body-like inclusions (LBIs) in the spinal cords of patients with sporadic amyotrophic lateral sclerosis (ALS) by… Expand
Amyotrophic cervical myelopathy in adolescence.
The clinical and radiological features in seven patients who had asymmetric muscular atrophy of the hand and forearm when young are reported and a new hypothesis for its aetiology is proposed.… Expand
NEUROFERRITINOPATHY IN A JAPANESE FAMILY WITH A DUPLICATION IN THE FERRITIN LIGHT CHAIN GENE
Neuroferritinopathy is a rare autosomal dominant movement disorder with the deposition of iron and ferritin within the basal ganglia. Four different pathogenic mutations in the ferritin light… Expand
Increased sympathetic outflow to muscles in patients with amyotrophic lateral sclerosis: a comparison with other neuromuscular patients
We investigated the effects of muscle loss and limitation of daily activities on sympathetic outflow to muscles by measuring muscle sympathetic nerve activity (MSNA) in 12 patients with amyotrophic… Expand
Clinical and histopathological features of progressive-type familial amyloidotic polyneuropathy with TTR Lys54
- T. Nagasaka, S. Togashi, H. Watanabe, Haruyasu Iida, Z. Shiozawa
- Journal of the Neurological Sciences
- 15 January 2009
The purpose of this study was to evaluate the clinical and pathological features in patients with progressive-type familial amyloidotic polyneuropathy (FAP) using autopsy and biopsy specimens. A… Expand
A single amino acid substitution within the mature sequence of ornithine aminotransferase obstructs mitochondrial entry of the precursor.
- T. Kobayashi, H. Ogawa, M. Kasahara, Z. Shiozawa, T. Matsuzawa
- Biology, Medicine
- American journal of human genetics
- 1 August 1995
We describe here evidence of congenital enzyme mistargeting induced not by abnormalities in the signal sequence. We examined the molecular mechanism of hereditary ornithine aminotransferase (OAT)… Expand
Effect of the free radical scavenger edaravone on peripheral nerve ischemia–reperfusion injury
We investigated the effects of edaravone, a free radical scavenger, on peripheral nerve ischemia–reperfusion injury caused by ligation of vessels supplying the sciatic and tibial nerves in rats. The… Expand
Sympathetic sudomotor and vasoconstrictive neural function in patients with Parkinson's disease.
- K. Shindo, Haruyasu Iida, H. Watanabe, E. Ohta, T. Nagasaka, Z. Shiozawa
- Parkinsonism & related disorders
- 1 November 2008
To evaluate sympathetic sudomotor and vasoconstrictive neural function in Parkinson's disease (PD), we simultaneously recorded sympathetic skin response (SSR) and skin blood flow (SVR; skin vasomotor… Expand
Intermittent penile erection in lumbar canal stenosis
Sirs: The clinical features of lumbar canal stenosis consist of dysaesthesias and pains in the legs, low back pains, difficulty in urinating and intermittent cauda equina claudication, when standing… Expand